Minimally Invasive Video-Assisted Surgical Management for Parapharyngeal Metastases From Papillary Thyroid Carcinoma: A Case Series Report
Minimally Invasive Video-Assisted Surgical Management for Parapharyngeal Metastases From Papillary Thyroid Carcinoma: A Case Series Report
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微创视频辅助手术治疗甲状腺乳头状癌咽旁转移瘤：病例系列报告
DOI：
10.3389/fonc.2019.01226
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发表时间：
2019-11
影响因子：
4.7
通讯作者：
Yu Ji-Chun
中科院分区：
文献类型：
--
作者：
Yu Shi-Tong;Chen Wan-Zhi;Xu De-Bin;Xie Rong;Zhou Tao;Yu Ji-Chun
背景：甲状腺乳头状癌（PTC）是内分泌系统中最常见的癌症类型。转移到咽旁淋巴结（PPLN）是罕见的。在此，我们报告了一个病例系列的PTC患者PPLN转移手术使用微创视频辅助（MIVA）技术，以评估这种技术的安全性和有效性。方法：在这项单机构研究中，2012年1月至2018年7月期间入组了6例连续的PPLN转移PTC患者。所有PPLN均采用MIVA技术治疗。结果：6例接受手术的患者（3名女性和3名男性）入组本研究。患者的中位年龄为40.5岁（39-66岁）。5例患者（83.3%）被诊断为原发性PTC伴PPLN转移，1例患者在首次PTC手术后17年PPLN PTC复发。所有患者均手术成功，中位手术时间185（100-280）min，出血量85（30-120）ml。除1例患者发生吞咽困难外，其他患者均未发生术后并发症，吞咽困难在3个月内消退。在15个月（10-31）的中位随访期间，没有患者表现出复发或持续性疾病。结论：MIVA经宫颈入路治疗PTC合并PPLN转移瘤技术可行、可靠、创伤小。未来的研究需要积累更多的经验，调查该技术的适应症，并确定长期的肿瘤安全性。
Background: Papillary thyroid carcinoma (PTC) is the most prevalent cancer type in the endocrine system. Metastases to parapharyngeal lymph nodes (PPLNs) are rare. Herein, we reported a case series of PTC patients with PPLN metastases operated on by using the minimally invasive video-assisted (MIVA) technique to evaluate the safety and effectiveness of this technique. Method: In this single-institutional study, six consecutive PTC patients with PPLN metastases between January 2012 and July 2018 were enrolled. All PPLNs were managed by the MIVA technique. Result: Six patients (three women and three men) who underwent surgery were enrolled in the current study. The median age of patients was 40.5 years (39–66). Five patients (83.3%) were diagnosed with primary PTC with PPLN metastases, and one patient had PTC recurrence in the PPLNs 17 years after her first PTC surgery. Surgical treatment was successful in all patients, and the median operative time and bleeding volume were 185 (100–280) min and 85 (30–120) ml, respectively. None of the patients experienced post-operative complications except for one patient who experienced dysphagia, which resolved within 3 months. During a median follow-up of 15 months (10–31), none of the patients exhibited recurrence or persistent disease. Conclusion: The MIVA transcervical approach was technically feasible and reliable, with less invasiveness for PTC patients with PPLN metastases. Future studies are needed to accumulate more experience, investigate the indications of the technique, and determine the long-term oncological safety.
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影响因子：
1.7
作者：
Z. Gooi;Raymand Lee;Kenneth K. Y. Wong;P. Tam
通讯作者：
Z. Gooi;Raymand Lee;Kenneth K. Y. Wong;P. Tam
影响因子：
2
作者：
L. Giordano;F. Pilolli;S. Toma;M. Bussi
通讯作者：
L. Giordano;F. Pilolli;S. Toma;M. Bussi
DOI：
10.1002/hed.20138
发表时间：
2004-12
期刊：
Head & Neck
影响因子：
--
作者：
M. Hamoir;G. Desuter
通讯作者：
M. Hamoir;G. Desuter
影响因子：
6.1
作者：
Xiaolei Wang;Zhengang Xu;Yue-huang Wu;Shaoyan Liu;Yue Yu
通讯作者：
Xiaolei Wang;Zhengang Xu;Yue-huang Wu;Shaoyan Liu;Yue Yu
影响因子：
2.4
作者：
J. Riley
通讯作者：
J. Riley