Risk factors for duodenal ulcer disease.
Risk factors for duodenal ulcer disease.
复制标题
十二指肠溃疡病的危险因素。
作者：
N. Farsakh
目标
在幽门螺杆菌感染率较高的约旦，评价一些传统危险因素对十二指肠溃疡患病率的作用。
方法
本研究于1998年1月至1999年7月期间在约旦伊尔比德约旦科技大学健康中心的内窥镜部门进行。患者组包括290例经内镜证实的十二指肠溃疡受试者，161例因各种适应症接受内镜检查并发现无溃疡的受试者被视为对照组。在手术前填写了经过验证的问卷，其中包含与年龄、性别、居住地区、溃疡家族史、血型、吸烟、咖啡和茶摄入以及膳食规律有关的数据。
结果
以下因素与溃疡患病率增加相关，男性，溃疡家族史，O型血，不吃早餐或一顿以上，咖啡摄入和吸烟。
结论
许多因素在幽门螺杆菌感染者的溃疡病易感性中是重要的。这些因素的修改将是必不可少的，以减少溃疡病的患病率，并将导致大量的经济和医疗储蓄。
OBJECTIVES
To evaluate the role played by some of the traditional risk factors on the prevalence of duodenal ulcer disease in Jordan, where the prevalence of Helicobacter pylori is high.
METHODS
This study was carried out in the Endoscopy unit at the Health Center, Jordan University of Science and Technology, Irbid, Jordan, during the period January 1998 through to july 1999. The patients' group consisted of 290 subjects with endoscopically proven duodenal ulcers and 161 subjects who were endoscoped for various indications and found to have no ulcers were considered as controls. Validated questionnaires were filled out before the procedure, containing data related to age, sex, area of residence, family history of ulcer, blood grouping, cigarette smoking, coffee and tea ingestion, and regularity of meals.
RESULTS
The following factors were associated with increased ulcer prevalence, male gender, family history of ulcer, blood group O, skipping breakfast or more than one meal, coffee ingestion and cigarette smoking.
CONCLUSIONS
Many factors are important in the predisposition for ulcer disease in subjects with Helicobacter pylori. Modification of these factors would be essential to decrease the prevalence of ulcer disease and will result in large economic and medical savings.