THE CHICKS MARGINAL ZONE AND PRIMITIVE STREAK FORMATION .1. COORDINATIVE EFFECT OF INDUCTION AND INHIBITION
THE CHICKS MARGINAL ZONE AND PRIMITIVE STREAK FORMATION .1. COORDINATIVE EFFECT OF INDUCTION AND INHIBITION
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DOI：
10.1016/0012-1606(89)90090-0
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发表时间：
1989-07-01
影响因子：
2.7
通讯作者：
EYALGILADI, H
中科院分区：
文献类型：
--
作者：
KHANER, O;EYALGILADI, H
在阶段X，XI和XII的后边缘区和侧边缘区片段的各种移植实验已经进行，以测试它们与原始条纹（PS）的发展的相关性。在所研究的阶段，边缘区（MZ）表现为环状梯度场，其最大值在后端（PM）。PM被认为是能够在促进PS的发展和抑制的MZ的其他区域的感应电位的同时。通过系统评价不同发育阶段的PMs的诱导和抑制能力，发现这两个特征在X阶段最大。在第十一和第十二阶段，这两个属性逐渐减少在MZ和建立在形成的下胚层。
A variety of transplantation experiments of posterior and lateral marginal zone fragments at astages X, XI, and XII have been carried out in order to test their relevance to the development of a primitive streak (PS). At the stages studied the marginal zone (MZ) was shown to behave as a ring-like gradient field, the maximal value of which was at the posterior end (PM). The PM was found to be capable at the same time of promoting the development of a PS and of suppressing the inductive potential of other regions of the MZ. By systematically evaluating inductive and suppressive capacities of PMs, at different developmental stages, it was found that both features are maximal at stage X. During stages XI and XII, both properties gradually decrease in the MZ and build up in the forming hypoblast.