Fear and the brain: Where have we been, and where are we going?
Fear and the brain: Where have we been, and where are we going?
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DOI：
10.1016/s0006-3223(98)00282-0
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发表时间：
1998-12-15
影响因子：
10.6
通讯作者：
LeDoux, J
中科院分区：
文献类型：
--
作者：
LeDoux, J
近年来，人们对情绪的神经基础产生了极大的兴趣。这种热情很大程度上是由对杏仁核及其对恐惧的影响的研究引发的。这项工作表明，杏仁核能够检测并组织对自然危险（如捕食者）的反应，并了解新的威胁和预测其发生的刺激。后一个过程已使用称为经典恐惧调节的程序进行了广泛研究。本文调查了在理解恐惧的神经基础及其对焦虑症的影响方面所取得的进展，以及我们的知识差距。生物精神病学 1998；44：1229-1238 (C) 1998 生物精神病学协会。
In recent years, there has been all explosion of interest ill the neural basis of emotion. Much of this enthusiasm has been triggered by studies of the amygdala and its contribution to fear. This work has shown that the amygdala detects and organizes responses to natural dangers (like predators) and learns about novel threats and the stimuli that predict their occurrence. The latter process has been studied extensively using a procedure called classical fear conditioning. This article surveys the progress that has been made in understanding the neural basis of fear and its implications for anxiety disorders, as well as the gaps in our knowledge. Biol Psychiatry 1998;44:1229-1238 (C) 1998 Society of Biological Psychiatry.