Defining Biobank
Defining Biobank
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DOI：
10.1089/bio.2013.0042
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发表时间：
2013-10-01
影响因子：
1.6
通讯作者：
Watson, Peter
中科院分区：
文献类型：
--
作者：
Hewitt, Robert;Watson, Peter
生物库一词于1996年首次出现在科学文献中，在接下来的五年里，主要用于描述基于人类种群的生物库。近年来，这一术语被用于更一般的意义，目前在报告、准则和规范性文件中有许多不同的定义。有些定义是概括性的，包括所有类型的生物样本收集设施。另一些则是特定的，仅限于人类样本的收集，有时仅限于基于人口的收集。为了帮助解决这一问题上的困惑，我们对参与管理各类样本收集的人员的意见进行了调查。这项调查是使用一份在线问卷进行的，共吸引了303份回复。结果表明，人们一致认为，生物库一词可用于人类、动物、植物或微生物样本的生物收集；生物库一词应仅适用于具有相关样本数据的样本收集，并适用于根据专业标准管理的收集。对于一个收藏的目的、规模或访问级别是否应该决定它是否被称为生物库，没有达成共识。从这些发现来看，我们认为，生物库的一般、广泛的定义将继续存在，现在应该把注意力集中在需要对不同的生物库类型进行普遍接受的、系统的分类。
The term biobank first appeared in the scientific literature in 1996 and for the next five years was used mainly to describe human population-based biobanks. In recent years, the term has been used in a more general sense and there are currently many different definitions to be found in reports, guidelines and regulatory documents. Some definitions are general, including all types of biological sample collection facilities. Others are specific and limited to collections of human samples, sometimes just to population-based collections. In order to help resolve the confusion on this matter, we conducted a survey of the opinions of people involved in managing sample collections of all types. This survey was conducted using an online questionnaire that attracted 303 responses. The results show that there is consensus that the term biobank may be applied to biological collections of human, animal, plant or microbial samples; and that the term biobank should only be applied to sample collections with associated sample data, and to collections that are managed according to professional standards. There was no consensus on whether a collection's purpose, size or level of access should determine whether it is called a biobank. Putting these findings into perspective, we argue that a general, broad definition of biobank is here to stay, and that attention should now focus on the need for a universally-accepted, systematic classification of the different biobank types.