Insomnia increases risk for cardiovascular events in women and in men with low socioeconomic status: A longitudinal, register-based study
Insomnia increases risk for cardiovascular events in women and in men with low socioeconomic status: A longitudinal, register-based study
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DOI：
10.1016/j.jpsychores.2014.02.001
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发表时间：
2014-04-01
影响因子：
4.7
通讯作者：
Ostergren, Per-Olof
中科院分区：
文献类型：
--
作者：
Canivet, Catarina;Nilsson, Peter M.;Ostergren, Per-Olof
目的：失眠、睡眠时间长短都与心血管疾病有关。男性和低社会经济地位也与心血管疾病有关，但尚不清楚这两个因素是否会改变睡眠不良对心血管疾病发病率的影响。（来自瑞典马尔莫的一般人群的年龄为45至64岁的5875名男性和7742名女性，无心血管疾病史;参与率为41%），随访至2005年或直至官方登记记录的首次心血管事件（定义为心肌梗死、中风或因缺血性心脏病导致的死亡）。将基线血压、体重指数、心理社会状况和自我报告的睡眠习惯的询问数据与心血管事件的风险比（HR）进行比较。在女性中，确认四种失眠症状中至少有一种是“中度”或“相当大”的问题与心血管事件有关（完全校正的HR 1.4 [95% CI 1.2-1.6]和人群归因分数17.3%）。过去或现在从事体力劳动的男性也是如此（HR 1.3 [95% CI 1.1-1.6]和人群归因分数11.8%）。HRs进一步增加，在妇女失眠症状相结合的短或长的睡眠时间。结论：失眠是一个重要的公共卫生问题，影响心血管疾病的发病率。考虑性别和社会经济地位是研究睡眠和心血管疾病结果的一种有价值的方法。(C)2014爱思唯尔公司All rights reserved.
Objectives: Insomnia and short and long sleep durations have all been linked to cardiovascular disease. Male gender and low socioeconomic status are also related to cardiovascular disease, but it is unclear whether these two factors modify the impact of poor sleep on cardiovascular disease incidence.Methods: Participants (5875 men and 7742 women ages 45 to 64 with no history of cardiovascular disease from the general population of Malmo, Sweden; participation rate 41%) were enrolled from 1992 to 1994 and followed until 2005 or until the first cardiovascular event (defined as myocardial infarction, stroke, or death due to ischemic heart disease), as recorded by official registers. Baseline blood pressure, BMI, and inquiry data concerning psychosocial circumstances and self-reported sleep habits were compared with hazard ratios (HRs) of cardiovascular events.Results: Affirming 'moderate' or 'considerable' problems with at least one out of the four insomnia symptoms was associated with cardiovascular event in women (fully-adjusted HR 1.4 [95% CI 1.2-1.6] and population attributable fraction 17.3%). The same was true of men with past or present manual occupation (HR 1.3 [95% CI 1.1-1.6] and population attributable fraction 11.8%). The HRs increased further in women where insomnia symptoms were combined with short or long sleep duration.Conclusions: Insomnia is a significant public health problem with implications for cardiovascular disease incidence. Taking gender and socioeconomic status into account is a worthwhile approach in research on sleep and cardiovascular disease outcomes. (C) 2014 Elsevier Inc. All rights reserved.