Challenges in the classification of pediatric multiple sclerosis and future directions
Challenges in the classification of pediatric multiple sclerosis and future directions
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儿科多发性硬化症分类的挑战和未来方向
DOI：
10.1212/01.wnl.0000259421.40556.76
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发表时间：
2007
期刊：
影响因子：
9.9
通讯作者：
E. Waubant
中科院分区：
文献类型：
--
作者：
A. Belman;T. Chitnis;C. Renoux;E. Waubant
为了改善对多发性硬化症（MS）儿童的护理，并通过合作研究促进对潜在生物学机制的了解，国际儿童多发性硬化症研究组提出了儿童多发性硬化症和相关中枢神经系统脱髓鞘疾病的病例定义标准。本文总结了在制定这些定义和提出的标准背后的理由时提出的问题，以及应用一套统一定义将促进的潜在的国际多中心研究。
To improve care for children with multiple sclerosis (MS) and to advance understanding of the underlying biologic mechanisms through collaborative research studies, criteria for case definitions of pediatric MS and related CNS demyelinating disorders were proposed by the International Pediatric MS Study Group. Issues raised during development of these definitions and rationale behind criteria proposed are summarized in this article, as are potential international multicenter research studies that would be facilitated by the application of a uniform set of definitions.