AMPLIFICATION AND ANALYSIS OF DNA-SEQUENCES IN SINGLE HUMAN-SPERM AND DIPLOID-CELLS
AMPLIFICATION AND ANALYSIS OF DNA-SEQUENCES IN SINGLE HUMAN-SPERM AND DIPLOID-CELLS
复制标题
DOI：
10.1038/335414a0
复制
发表时间：
1988-09-29
期刊：
影响因子：
64.8
通讯作者：
ARNHEIM, N
中科院分区：
文献类型：
--
作者：
LI, HH;GYLLENSTEN, UB;ARNHEIM, N
使用聚合酶链反应分析DNA序列在个别二倍体细胞和人类精子表明，两个遗传基因座可以从一个精子共扩增，这可能允许分析以前无法访问的遗传现象。
The use of the polymerase chain reaction for analysing DNA sequences in individual diploid cells and human sperm shows that two genetic loci can be co-amplified from a single sperm, which may allow the analysis of previously inaccessible genetic phenomena.