Additional proof of reduction of ethanol absorption from rat intestine in vivo by high acetaldehyde concentrations.
Additional proof of reduction of ethanol absorption from rat intestine in vivo by high acetaldehyde concentrations.
复制标题
高乙醛浓度可减少大鼠体内乙醇吸收的额外证据。
DOI：
10.1093/oxfordjournals.alcalc.a045752
复制
发表时间：
1995
影响因子：
2.8
通讯作者：
K. Ameno
中科院分区：
文献类型：
--
作者：
H. Kinoshita;I. Ijiri;S. Ameno;C. Fuke;K. Ameno
我们研究了用生理盐水、氰胺、4-甲基吡唑和氰胺+ 4-甲基吡唑预处理的大鼠的肠乙醇吸收。吸收速率常数的值在氰胺预处理组与高乙醛水平是最低的四个组中，但有没有显着差异，其余各组之间。我们发现，高乙醛浓度本身明显减少肠道乙醇吸收。
We investigated intestinal ethanol absorption in rats pretreated with saline, cyanamide, 4-methylpyrazole and cyanamide + 4-methylpyrazole. The value of the absorption rate constant in the cyanamide-pretreated group with high acetaldehyde levels was the lowest among the four groups, but there were no significant differences among the remaining groups. We found that high acetaldehyde concentration itself clearly reduces intestinal ethanol absorption.