Magnetic resonance imaging in the management of Crohn's disease: a systematic review and meta-analysis.
Magnetic resonance imaging in the management of Crohn's disease: a systematic review and meta-analysis.
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DOI：
10.1186/s13244-021-01064-9
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发表时间：
2021-08-18
影响因子：
4.7
通讯作者：
Abduljabbar AH
中科院分区：
文献类型：
--
作者：
Ahmad R;Ajlan AM;Eskander AA;Alhazmi TA;Khashoggi K;Wazzan MA;Abduljabbar AH
克罗恩病 (CD) 是一种可发生在胃肠道任何部位的疾病，但通常形成于结肠和回肠末端。磁共振成像（MRI）已成为评估小肠活动的有益方式。本研究报告了磁共振肠造影的系统回顾和荟萃分析，用于预测 CD 活动并评估结果和可能的并发症。根据PRISMA指南，根据QUADAS-II评分 ≥ 9，共筛选了25项已确定CD的低风险研究。19项研究的汇总分析显示敏感性为90%，异质性为χ2 = 81.83，I2为80.3%。另外，计算出特异性为89%，异质性为χ2 =≥65.12，I2为70.0%。结论是，MRI 提供了 CT 小肠造影的有效替代方案，可在放射科医生的监督下检测 CD 患者的小肠活动，以评估疾病活动及其并发症。其优点包括避免辐射暴露和良好的诊断准确性。
Crohn’s disease (CD) is a condition that can occur in any part of the gastrointestinal tract, although usually forms in the colon and terminal ileum. Magnetic resonance imaging (MRI) has become a beneficial modality in the evaluation of small bowel activity. This study reports on a systematic review and meta-analysis of magnetic resonance enterography for the prediction of CD activity and evaluation of outcomes and possible complications. Following the PRISMA guidelines, a total of 25 low-risk studies on established CD were selected, based on a QUADAS-II score of ≥ 9. A sensitivity of 90% was revealed in a pooled analysis of the 19 studies, with heterogeneity of χ2 = 81.83 and I2 of 80.3%. Also, a specificity of 89% was calculated, with heterogeneity of χ2 = 65.12 and I2 of 70.0%. It was concluded that MRI provides an effective alternative to CT enterography in the detection of small bowel activity in CD patients under supervision of radiologist for assessment of disease activity and its complications. Its advantages include the avoidance of radiation exposure and good diagnostic accuracy.
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