SYNTHESIS OF UDP-GALACTOSAMINE AND UPD-N-ACETYLGALACTOSAMINE
SYNTHESIS OF UDP-GALACTOSAMINE AND UPD-N-ACETYLGALACTOSAMINE
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DOI：
10.1016/0006-291x(70)90586-3
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发表时间：
1970-01-01
影响因子：
3.1
通讯作者：
MALEY, F
中科院分区：
文献类型：
--
作者：
MALEY, F
将市售半乳糖-1-磷酸尿基转移酶用于合成UDP-氨基半乳糖和UDP-N-乙酰氨基半乳糖。该方法提供了一种相对简单的方法，用于高产率地制备这些重要的生物材料，并且以几乎任何所需的特定放射性的同位素形式，单独标记或组合标记。也支持先前提出的氨基半乳糖在大鼠肝脏中的代谢途径。
A commercially available preparation of galactose-1-phosphateuridyl transferase was used in the synthesis of UDP-galactosamine and UDP-N-acetylgalactosamine. The method provides a relatively simple means for preparing these important biological materials in high yield and in an isotopic form of almost any desired specific radioactivity, labeled singly or in combination. Support for the route of metabolism of galactosamine in rat liver proposed previously is also presented.