Exploring the Impact of Chronic Tic Disorders on Youth: Results from the Tourette Syndrome Impact Survey
Exploring the Impact of Chronic Tic Disorders on Youth: Results from the Tourette Syndrome Impact Survey
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DOI：
10.1007/s10578-010-0211-4
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发表时间：
2011-04-01
影响因子：
2.9
通讯作者：
Walkup, John
中科院分区：
文献类型：
--
作者：
Conelea, Christine A.;Woods, Douglas W.;Walkup, John
先前的研究表明，慢性抽动障碍（CTD）与多个领域的功能损害有关。然而，方法上的限制，如通过父母报告获得的数据，儿童和成人样本汇总的数据集，以及寻求治疗的小样本，限制了解释。目前的研究在一个大型的“虚拟”社区样本中探讨了抽搐对年轻人的功能影响。一项基于互联网的调查由患有CTD的孩子的家庭完成。样本包括740名父母和232名他们的孩子（10-17岁）。该调查评估了五个功能领域的影响：身体、社会、家庭、学术和心理。还评估了与健康有关的生活质量和抽搐引起的歧视的看法。结果表明：(1)青少年CTD患者有轻至中度的功能障碍，(2)功能障碍与抽动严重程度普遍呈正相关，(3)儿童CTD合并一种或多种精神疾病往往有更大的功能障碍，(4)青少年CTD患者有显著比例因抽动而受到歧视。讨论了这些发现的意义和局限性。
Prior research has demonstrated that chronic tic disorders (CTD) are associated with functional impairment across several domains. However, methodological limitations, such as data acquired by parental report, datasets aggregated across child and adult samples, and small treatment-seeking samples, curtail interpretation. The current study explored the functional impact of tics among youth in a large, "virtual" community sample. An Internet-based survey was completed by families with children who had CTD. The sample included 740 parents and 232 of their children (ages 10-17 years). The survey assessed impact across five functional domains: physical, social, familial, academic, and psychological. Health-related quality of life and perceptions of discrimination resulting from tics were also assessed. Results suggest that (1) youth with CTD experience mild to moderate functional impairment, (2) impairment is generally positively correlated with tic severity, (3) children with CTD plus one or more co-occurring psychiatric conditions tend to have greater functional impairment, and (4) a notable portion of youth with CTD experience discrimination due to tics. Implications and limitations of these findings are discussed.