Severe Acute Fibrinous and Organizing Pneumonia with Acute Respiratory Distress Syndrome
Severe Acute Fibrinous and Organizing Pneumonia with Acute Respiratory Distress Syndrome
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DOI：
10.4046/trd.2011.71.5.368
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发表时间：
2011-11-01
影响因子：
2.9
通讯作者：
Cho, Young-Jae
中科院分区：
文献类型：
--
作者：
Kang, Hyo Jae;Choi, Sun Mi;Cho, Young-Jae
急性化脓性机化性肺炎是一种新认识的急性肺损伤类型。一位49岁女性，因咳嗽和劳力性呼吸困难加重就诊。除暴露于家用加湿器（含灭菌器）外，无吸烟史，无特定既往病史。胸部计算机断层扫描显示右下叶斑片状实变伴纤维化，双肺小叶中心磨玻璃样阴影边界不清。病理学表现为肺实质斑片状区域，肺泡管和肺泡内纤维蛋白沉积，肺泡腔内纤维蛋白球和含铁血黄素沉积。我们病例的组织学类型与弥漫性肺泡损伤（缺乏透明膜）和嗜酸性粒细胞缺乏（缺乏嗜酸性粒细胞）相鉴别。在我们的病例中，患者接受了
Acute fibrinous and organizing pneumonia is a newly recognized pattern of acute lung injury. A 49-year-old female presented with a cough and worsening dyspnea on exertion. She had no history of smoking and no specific past medical history except exposure of home humidifier containing sterilizer. A chest computed tomography scan showed patchy consolidation with fibrosis in the right lower lobe and ill-defined centrilobular ground glass opacity in both lungs. The pathological findings were patchy areas of lung parenchyma with fibrin deposits in the alveolar ducts and alveoli, and fibrin balls with hemosiderin deposition in the alveolar spaces. The histological pattern of our case is differentiated from diffuse alveolar damage by the absence of hyaline membranes, and from eosinophilic pneumonia by the lack of eosinophils. In our case, the patient was treated with