A convenient method for preparing aromatic ketones from acyl chlorides and arylboronic acids via Suzuki-Miyaura type coupling reaction
A convenient method for preparing aromatic ketones from acyl chlorides and arylboronic acids via Suzuki-Miyaura type coupling reaction
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DOI：
10.1016/s0040-4039(02)02501-7
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发表时间：
2003-01-06
影响因子：
1.8
通讯作者：
Ogura, K
中科院分区：
文献类型：
--
作者：
Urawa, Y;Ogura, K
以甲苯为溶剂，水合K3PO4为催化剂，钯催化硼酸与酰氯的交叉偶联反应，有效地合成了芳香酮。这允许使用脂族酰氯作为起始材料。水合水作为激活催化系统的H2O来源发挥着重要作用。(C)2002爱思唯尔科技有限公司版权所有。
Aromatic ketones are synthesized efficiently via palladium-catalyzed cross-coupling reaction of boronic acids with acyl chlorides in the presence of K3PO4 hydrate in toluene. This allows the use of aliphatic acyl chlorides as the starting material. Hydrated water plays a significant role as an H2O source to activate the catalytic system. (C) 2002 Elsevier Science Ltd. All rights reserved.