Prevalence, severity, and chronicity of pain and general health-related quality of life in patients with localized prostate cancer
Prevalence, severity, and chronicity of pain and general health-related quality of life in patients with localized prostate cancer
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DOI：
10.1016/j.ejpain.2007.07.006
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发表时间：
2008-04-01
影响因子：
3.6
通讯作者：
Sabatowski, Rainer
中科院分区：
文献类型：
--
作者：
Gerbershagen, Hans J.;Oezguer, Enver;Sabatowski, Rainer
目的：分析的患病率和疼痛的严重程度谱及其关系，以健康相关的生活质量和生物，心理，社会后果的疼痛患者之间的根治性pneumectomy.Methods：泌尿科住院患者完成了流行病学疼痛问卷调查，广泛探索术前急性和慢性疼痛在21个身体区域。使用von Korfrs疼痛分级（CPGQ）确定疼痛的严重程度。采用美因茨疼痛分期系统（MPSS）估计疼痛慢性化。焦虑和抑郁症状与HADS和习惯幸福感问卷（FW-7）确定。使用SF-12测量健康相关生活质量。合并症和合并症相关的日常活动的干扰与加权疾病检查表（WICL.Results）确定：80的115例（69.6%）报告疼痛，在过去3个月术前。28.7%的疼痛患者与泌尿系疾病有关。根据CPGQ疼痛3级和4级确定的重度功能失调性疼痛分别为20%和13.8%。以MPSS II级和III级疼痛为特征的晚期慢性疼痛分别占38.8%和11.3%。无疼痛主诉的局限性前列腺癌患者的健康相关生活质量和习惯性幸福感明显更好，焦虑和抑郁评分更低，合并症更少。癌症相关疼痛和非癌症疼痛患者在疼痛慢性化、疼痛严重程度、疼痛强度、焦虑、合并症和身体健康方面没有差异（SF 12-PCS）.结论：癌症患者在预定的根治性乳房切除术前严重和慢性疼痛的高患病率-结合相当大的残疾影响和明显降低的生活质量，需要进行短期的常规筛查-分析疼痛和精神病理学的严重程度谱。患者自评疼痛慢性分期和心理困扰分析将允许疾病严重程度指导治疗和预防痛苦和额外的新的慢性术后疼痛。(C)2007年，国际疼痛研究协会欧洲分会联合会。由爱思唯尔有限公司出版。保留所有权利。
Aims: To analyze the prevalence and the severity spectrum of pain and its relationships to health-related quality of life and the bio-psycho-social consequences of pain among patients scheduled for radical prostatectomy.Methods: Urological inpatients completed an epidemiological pain questionnaire extensively exploring pre-operative acute and chronic pains in 21 body regions. The severity of pain was determined using von Korfrs Pain Grading (CPGQ). Pain chronicity was estimated employing the Mainz Pain Staging System (MPSS). Anxiety and depressive symptoms were identified with the HADS and the Habitual Well-Being Questionnaire (FW-7). Health-related quality of life was measured using the SF-12. Comorbidities and comorbidity-related interferences with daily activities were ascertained with the Weighted Illness Checklist (WICL).Results: Eighty of 115 patients (69.6%) reported about pain during the last 3 months pre-operatively. 28.7% of the pain patients had pain related to urological disease. Severe dysfunctional pain was identified by pain Grades 3 and 4 of the CPGQ in 20% and 13.8%, respectively. Advanced pain chronicity characterized by pain Stages II and III of the MPSS was present in 38.8% and 11.3%. Patients with localized prostate cancer without pain complaints had significantly better health-related quality of life and habitual well-being and lower anxiety and depression scores and fewer comorbidities. Patients with cancer-related and non-cancer pain did not differ in pain chronicity, pain severity, pain intensities, anxiety, comorbidities and physical health (SF12-PCS).Conclusions: The high prevalence of severe and chronic pain in cancer patients before scheduled radical prostatectomy - combined with considerable disability effects and markedly reduced quality of life necessitate a short routine screening-analysis of the severity spectrum of pain and psychopathology. Patient self-rated pain chronicity staging and psychological distress analysis will allow a disorder severity-guided treatment and the prevention of suffering and additional new chronic post-surgical pain. (C) 2007 European Federation of Chapters of the International Association for the Study of Pain. Published by Elsevier Ltd. All rights reserved.