Walking versus running for hypertension, cholesterol, and diabetes mellitus risk reduction.
Walking versus running for hypertension, cholesterol, and diabetes mellitus risk reduction.
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DOI：
10.1161/atvbaha.112.300878
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发表时间：
2013-05
期刊：
影响因子：
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通讯作者：
Thompson PD
中科院分区：
文献类型：
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作者：
Williams PT;Thompson PD
为了测试中等强度（例如，步行）和剧烈运动（例如，跑步）提供同等的健康益处。我们使用了全国跑步者（n= 33，060）和步行者（n= 15，945）健康研究队列，以检查运动模式的差异以及运动强度对冠心病（CHD）危险因素的影响。在6.2年随访期间，将基线支出（METhr/d）与自我报告的、医生诊断的高血压、高胆固醇血症、糖尿病和CHD事件进行比较。每次METh/d跑步可显著降低高血压发病风险4.2%（P<10-7）、高胆固醇血症4.3%（P<10-14）、糖尿病12.1%（P<10-5）和冠心病4.5%（P=0.05）。步行的相应减少分别为7.2%（P<10-6）、7.0%（P<10-8）、12.3%（P<10-4）和9.3%（P=0.01）。相对于<1.8 METh/d，1.8 ~ 3.6、3.6 ~ 5.4、5.4 ~ 7.2和≥ 7.2 METh/d的高胆固醇血症风险降低分别为：1）跑步10.1%、17.7%、25.1%和34.9%，步行14.0%、23.8%、21.8%和38.3%;（2）运动组、步行组和步行组分别为19.7%、19.4%、26.8%和39.8%、14.7%、19.1%、23.6%和13.3%;（3）糖尿病患者中，运动组分别为43.5%、44.1%、47.7%和68.2%，步行组分别为34.1%、44.2%和23.6%（步行> 5.4METh/d的糖尿病患者极少）。对于糖尿病（P=0.94）或冠心病（P=0.26），跑步的风险降低并不显著大于步行，对于高血压（P=0.06）和高胆固醇血症（P=0.04），步行的风险降低仅略大于跑步。中度（步行）和剧烈（跑步）运动的等效能量消耗对高血压、高胆固醇血症、糖尿病和CHD的风险降低相似，但对CHD进行结论性评估的统计学能力有限。
To test whether equivalent energy expenditure by moderate-intensity (e.g., walking) and vigorous-intensity exercise (e.g., running) provides equivalent health benefits. We used the National Runners’ (n=33,060) and Walkers’ (n=15,945) Health Study cohorts to examine the effect of differences in exercise mode and thereby exercise intensity on coronary heart disease (CHD) risk factors. Baseline expenditure (METhr/d) was compared to self-reported, physician-diagnosed incident hypertension, hypercholesterolemia, diabetes and CHD during 6.2 years follow-up. Running significantly decreased the risks for incident hypertension by 4.2% (P<10-7), hypercholesterolemia by 4.3% (P<10-14), diabetes by 12.1% (P<10-5), and CHD by 4.5% per METh/d run (P=0.05). The corresponding reductions for walking were 7.2% (P<10-6), 7.0% (P<10-8), 12.3% (P<10-4), and 9.3% (P=0.01). Relative to <1.8 METh/d, the risk reductions for 1.8 to 3.6, 3.6 to 5.4, 5.4 to 7.2, and ≥ 7.2 METh/d were: 1) 10.1%, 17.7%, 25.1% and 34.9% from running and 14.0%, 23.8%, 21.8% and 38.3% from walking for hypercholesterolemia; 2) 19.7%, 19.4%, 26.8% and 39.8% from running and 14.7%, 19.1%, 23.6% and 13.3% from walking for hypertension; 3) 43.5%, 44.1%, 47.7% and 68.2% from running and 34.1%, 44.2%, and 23.6% from walking for diabetes (too few cases for diabetes for walking >5.4 METh/d). The risk reductions were not significantly greater for running than walking for diabetes (P=0.94) or CHD (P=0.26), and only marginally greater for walking than running for hypertension (P=0.06) and hypercholesterolemia (P=0.04). Equivalent energy expenditures by moderate (walking) and vigorous (running) exercise produced similar risk reductions for hypertension, hypercholesterolemia, diabetes, and CHD, but there is limited statistical power to evaluate CHD conclusively.