Unusual cause of fever and diarrhea in a patient with AIDS - Penicillium marneffei infection

Unusual cause of fever and diarrhea in a patient with AIDS - Penicillium marneffei infection
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DOI:
10.1007/bf02088239
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发表时间:
1996-06-01
影响因子:
3.1
通讯作者:
Lai, CKW
Lai, CKW
中科院分区:
医学3区
文献类型:
--
作者:
Leung, R;Sung, JY;Lai, CKW

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近年来,在艾滋病患者中,有越来越多的由马尔尼菲氏杆菌(一种二形真菌)引起的机会性感染的报道(1-3)。大多数病例发生在曾在东南亚居住或旅行的患者中。事实上,青霉菌病被认为是亚洲的地方性疾病,在泰国北部已成为继肺外结核和隐球菌脑膜炎之后艾滋病的第三大常见机会性感染(3)。我们报告了一位中国艾滋病患者,他表现为青霉菌结肠炎,对两性霉素B和伊曲康唑治疗有反应。
There has been an increase in the number of reports of opportunistic infections by P. marneffei, a dimorphic fungus, among AIDS patients in recent years (1-3). The majority of cases occurred in patients who had lived in (3-5) or traveled to (1) Southeast Asia. Indeed, penicilliosis is thought to be endemic in Asia and has become the third most common opportunistic infection in AIDS after extrapulmonary tuberculosis and cryptococcal meningitis in northern Thailand (3). We report a Chinese patient with AIDS who presented with penicillium colitis that responded to a course of amphotericin B and itraconazole.