The Effect of Technology-Mediated Diabetes Prevention Interventions on Weight: A Meta-Analysis.
The Effect of Technology-Mediated Diabetes Prevention Interventions on Weight: A Meta-Analysis.
复制标题
DOI：
10.2196/jmir.4709
复制
发表时间：
2017-03-27
影响因子：
7.4
通讯作者：
Richardson CR
中科院分区：
文献类型：
--
作者：
Bian RR;Piatt GA;Sen A;Plegue MA;De Michele ML;Hafez D;Czuhajewski CM;Buis LR;Kaufman N;Richardson CR
以减肥为目标的生活方式干预措施，如通过糖尿病预防计划提供的干预措施，可降低患2型糖尿病的风险。技术介导的干预措施可能是一种选择，以帮助克服障碍，以计划交付，并在更大范围内传播糖尿病预防计划。我们进行了一项荟萃分析，以评估这种技术介导的干预措施对减肥的影响。在这项荟萃分析中，检索了6个数据库，以确定报告体重变化的研究，这些研究使用技术来介导饮食和运动干预，并针对2型糖尿病高风险人群。纳入了2002年1月1日至2016年8月4日期间发表的研究。检索识别出1196篇引文。其中，15项研究符合纳入标准，并评估了18项技术介导的干预措施，共计2774名参与者。研究持续时间为12周至2年。一项随机效应荟萃分析显示，干预措施的合并体重减轻效应为3.76千克（95% CI 2.8-4.7; P<.001）。几项研究还报告了干预后血糖控制的改善。小样本量和异质性的试验排除了技术介导的干预方法是最有效的评价。技术介导的糖尿病预防计划可以导致临床上显著的体重减轻，以及糖尿病前期患者的高血压改善。由于其大规模实施的潜力，这些干预措施将在糖尿病预防计划的传播中发挥重要作用。
Lifestyle interventions targeting weight loss, such as those delivered through the Diabetes Prevention Program, reduce the risk of developing type 2 diabetes. Technology-mediated interventions may be an option to help overcome barriers to program delivery, and to disseminate diabetes prevention programs on a larger scale. We conducted a meta-analysis to evaluate the effect of such technology-mediated interventions on weight loss. In this meta-analysis, six databases were searched to identify studies reporting weight change that used technology to mediate diet and exercise interventions, and targeted individuals at high risk for developing type 2 diabetes. Studies published between January 1, 2002 and August 4, 2016 were included. The search identified 1196 citations. Of those, 15 studies met the inclusion criteria and evaluated 18 technology-mediated intervention arms delivered to a total of 2774 participants. Study duration ranged from 12 weeks to 2 years. A random-effects meta-analysis showed a pooled weight loss effect of 3.76 kilograms (95% CI 2.8-4.7; P<.001) for the interventions. Several studies also reported improved glycemic control following the intervention. The small sample sizes and heterogeneity of the trials precluded an evaluation of which technology-mediated intervention method was most efficacious. Technology-mediated diabetes prevention programs can result in clinically significant amounts of weight loss, as well as improvements in glycaemia in patients with prediabetes. Due to their potential for large-scale implementation, these interventions will play an important role in the dissemination of diabetes prevention programs.