Oriented crystal growth of phenylalanine and a dipeptide by solution shearing
Oriented crystal growth of phenylalanine and a dipeptide by solution shearing
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DOI：
10.1039/d0tc01208d
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发表时间：
2020-07
影响因子：
6.4
通讯作者：
Kazunori Motai;Takuma Narimatsu;Chen Chen-Chen;Y. Hayamizu
中科院分区：
文献类型：
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作者：
Kazunori Motai;Takuma Narimatsu;Chen Chen-Chen;Y. Hayamizu
多肽的自组装结构由于其独特的电学和光学性质而受到广泛关注。该领域的挑战之一是在基底上形成取向的纳米结构。对于更实际的电气应用，至关重要的是在衬底上形成它们的薄膜，而不会由于随机取向而失去它们的固有物理特性。在这里，我们已经开发出一种技术，形成薄膜的结晶氨基酸和二肽的溶液剪切。我们已经使用偏振拉曼光谱和X射线衍射（XRD）测量的薄膜的特征。拉曼光谱显示，溶液剪切允许我们通过控制晶体取向沿着剪切方向在Si晶片上形成结晶氨基酸和二肽。XRD光谱支持了拉曼光谱的结果，也揭示了晶体在面外方向的择优取向。结果表明，溶液剪切抑制了多晶型的形成。这种形成取向生物分子薄膜的新方法有助于其在未来的生物电子应用。
Self-assembled structures of peptides have been recently gaining fundamental interest due to their unique electrical and optical properties arising from the variety of nanostructures. One of the challenges in this field is the formation of oriented nanostructures on a substrate. For more practical electrical applications, it is crucial to form their thin film on a substrate without losing their intrinsic physical properties due to random orientation. Here, we have developed a technique to form thin films of crystalized amino acids and dipeptides by solution shearing. We have characterized the thin films using polarized Raman spectroscopy and X-ray diffraction (XRD) measurements. Raman spectra revealed that the solution shearing allows us to form crystalline amino acids and dipeptides on Si wafers through control of crystal orientation along the direction of shearing. The XRD spectra supported the results of Raman spectroscopy, and also revealed the preferred orientation of the crystals in the out-of-plane direction. Futhermore, their polymorph formation was found to be suppressed by the solution shearing. This new approach to the formation of an aligned biomolecular thin film can be helpful for its bioelectronic applications in the future.