Using Reflectometric Interference Spectroscopy to Real-time Monitor Amphiphile-induced Orientational Responses of Liquid Crystals-loaded Silica Colloidal Crystal Films.
Using Reflectometric Interference Spectroscopy to Real-time Monitor Amphiphile-induced Orientational Responses of Liquid Crystals-loaded Silica Colloidal Crystal Films.
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DOI：
10.1021/acs.analchem.0c02749
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发表时间：
2020-08
影响因子：
7.4
通讯作者：
Lele Zhou;Qianqian Su;Feng Wu;Yizhen Wan;Pengfei Xu;Ao Dong;Qiang Li;Weiping Qian
中科院分区：
文献类型：
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作者：
Lele Zhou;Qianqian Su;Feng Wu;Yizhen Wan;Pengfei Xu;Ao Dong;Qiang Li;Weiping Qian
开发了一种基于干涉效应的光学转换和放大两亲物触发的液晶（LC）取向响应的方法。通过将 4´-戊基-4-氰基联苯 (5CB) 装入三维有序二氧化硅胶体晶体 (SCC) 薄膜中来实现敏感基板。基板光学厚度 (ΔOT) 的变化（由法布里-珀罗条纹反转）取决于液晶取向差异引起的折射率变化。加载到 SCC 薄膜中的 LC 的方向变化具有放大信号的作用。这些基于表面活性剂（烷基三甲基卤化铵（CnTAB，n=8、10、12、14 和 16）和十二烷基磺酸钠 (SLS)）和 LC 之间的相互作用，诱导 LC 分子的特定方向。在该流动系统中，两亲物吸附信号响应的可逆性与表面活性剂链的长度及其临界胶束浓度（CMC）有关。完成了一种基于液晶渗透 SCC 膜实时感测吸附物触发的锚定转变的新方法。这些结果为基于干涉效应的流动环境中分子及其相互作用的在线、免标记、实时分析提供了基础和原理。
An approach to optical transduction and amplification of amphiphile-triggered orientational responses of liquid crystals (LCs) based on interference effect was developed. The sensitive substrate was accomplished by lading 4´-pentyl-4-cyanobiphenyl (5CB) into three-dimensionally ordered silica colloidal crystal (SCC) films. Changes in the optical thickness (ΔOT) of the sub-strates, which are inverted by their Fabry-Perot fringes, depend on the changes of the refractive index caused by the differ-ences in the orientations of LCs. The orientation changes of LCs loading into SCC films have the effect of amplifying signals. These are based on the interactions between surfactants (alkyltrimethylammonium halides (CnTABs, n=8, 10, 12, 14, and 16) and sodium lauryl sulfonate (SLS)) and LCs which induce to a particular orientation of the LCs molecules. In this flowing sys-tem, the reversibility of signal response for adsorption of amphiphile was related to the length of the surfactant chain and its critical micelle concentration (CMC). A new method capable of real-time sensing adsorbate-triggered anchoring transitions based on LCs-infiltrated SCC films was accomplished. These results provide basics and principles for on-line, label-free and real-time analyzing of molecules and their interactions in flowing environment based on interference effect.