ULTRASOUND AND DENSITOMETRY OF THE CALCANEUS CORRELATE WITH THE FAILURE LOADS OF CADAVERIC FEMURS
ULTRASOUND AND DENSITOMETRY OF THE CALCANEUS CORRELATE WITH THE FAILURE LOADS OF CADAVERIC FEMURS
复制标题
DOI：
10.1007/bf00296338
复制
发表时间：
1995-02-01
影响因子：
4.2
通讯作者：
HAYES, WC
中科院分区：
文献类型：
--
作者：
BOUXSEIN, ML;COURTNEY, AC;HAYES, WC
我们使用双能X线骨密度仪（DXA）评估了16组匹配的尸体股骨近端和足部的骨密度（BMD）。我们还通过DXA扫描估计了股骨颈长度。定量超声密度测定法用于测量每只脚跟骨中的声速和宽带超声衰减（BUA）。然后，在设计用于模拟坠落撞击大转子的载荷配置中，对股骨近端进行失效测试。股骨颈BMD和转子BMD与股骨失效载荷密切相关（r（2）分别为0.79和0.81; P < 0.001），而股骨颈长度与股骨失效载荷中度相关（r（2）= 0.27，P = 0.04）。跟骨BMD（r（2）= 0.63，P < 0.001）和BUA（r（2）= 0.51，P = 0.002）也与股骨失效载荷显著相关。由于样本量较小，我们无法检测到独立参数与股骨失效载荷之间相关性强度的差异。采用多元线性回归分析，股骨颈BMD和股骨颈长度的组合是股骨失效载荷的最强预测因素（R（2）= 0.85，P < 0.001）。因此，似乎股骨和跟骨骨矿物质的性质可能是有用的，以确定那些人在髋部骨折的最大风险。
We assessed the bone mineral density (BMD) of 16 matched sets of cadaveric proximal femurs and feet using dual-energy x-ray absorptiometry (DXA). We also estimated the femoral neck length from the DXA scans. Quantitative ultrasound densitometry was used to measure the velocity of sound and broadband ultrasound attenuation (BUA) in the calcaneus of each foot. The proximal femurs were then tested to failure in a loading configuration designed to simulate a fall with impact to the greater trochanter. Femoral neck BMD and trochanteric BMD were strongly associated with the femoral failure load (r(2) = 0.79 and 0.81, respectively; P < 0.001), whereas femoral neck length was modestly correlated with femoral failure load (r(2) = 0.27, P = 0.04). Calcaneal BMD (r(2) = 0.63, P < 0.001) and BUA (r(2) = 0.51, P = 0.002) were also significantly associated with femoral failure load. Given the small sample size, we were unable to detect differences in the strength of the correlations between the independent parameters and femoral failure load. Using linear multiple regression analyses, the strongest predictor of femoral failure load was a combination of femoral neck BMD and femoral neck length (R(2) = 0.85, P < 0.001). Thus, it appears that both femoral and calcaneal bone mineral properties may be useful for identifying those persons at greatest risk for hip fracture.