Epidemiological factors and survival experience in 1770 children with acute leukemia treated by members of children's study group a between 1957 and 1964
Epidemiological factors and survival experience in 1770 children with acute leukemia treated by members of children's study group a between 1957 and 1964
复制标题
1957年至1964年儿童研究组a组成员治疗的1770例急性白血病儿童的流行病学因素及生存经历
作者：
M. Pierce;W. Borges;R. Heyn;J. Wolff;E. Gilbert
在一组1770名急性白血病儿童中，在11个与儿童癌症A组相关的儿科中心接受治疗，手术数据与诊断时的年龄、形态学类型、发病时的白细胞计数和诊断年份有关。儿童白血病3种形态类型的年龄分布不同。急性淋巴细胞白血病的特征是2 ~ 3岁时出现峰值，2 ~ 5岁时出现宽基线，而其他形态学类型则无此峰值。白人和黑人儿童的年龄分布相似。最有利的预后被发现在儿童急性淋巴细胞白血病谁是2至6岁的诊断，其中白细胞计数低于4,000/mm 3在发病时。1957年至1964年，在延长所有急性淋巴细胞白血病儿童的中位生存时间方面取得了进展，但其他类型的白血病却没有。在此期间，所有类型的白血病的10%生存率都有所提高。
In a group of 1770 children with acute leukemia, treated in 11 pediatric centers associated with Children's Cancer Group A, surgical data was related to age at diagnosis, morphological type, the leukocyte count at onset, and the year of diagnosis. The age distribution was different in the 3 morphological types of childhood leukemia. A peak at the age 2 to 3 years, with a broad base extending from 2 to 5 years, was characteristic of acute lymphoid leukemia, while the peak was absent in other morphological types. The age distribution was similar in Caucasian and Negro children. The most favorable prognosis was found in children with acute lymphoid leukemia who were 2 to 6 years of age at diagnosis in whom the leukocyte counts were below 4,000/mm3 at onset. Progress in extending the median survival time of all children with acute lymphoid but not other types of leukemia was noted between 1957 and 1964. The 10% survival figure improved for all types of leukemia during this period.