Determinants of health-related quality of life in coronary artery disease patients:: A prospective study generating a structural equation model
Determinants of health-related quality of life in coronary artery disease patients:: A prospective study generating a structural equation model
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DOI：
10.1176/appi.psy.46.3.212
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发表时间：
2005-06-01
期刊：
影响因子：
3.4
通讯作者：
Doering, S
中科院分区：
文献类型：
--
作者：
Höfer, S;Benzer, W;Doering, S
作者使用结构方程模型对冠心病患者的HRQL概念模型进行了检验。该模型包括生物医学因素以及个人和环境特征，在一个由465名患者组成的多中心小组中进行了三个时间点的测试(胸痛的基线评估以及1个月和3个月的随访)。随着时间的推移，该模型获得了令人满意的拟合。抑郁和焦虑症状对HRQL的影响最显著。HRQL和中介因素是不同的现象。作者认为，如果认为HRQL是一种临床结果，那么在临床常规中应考虑中介因素，特别是抑郁和焦虑症状。
The authors used structural equation modeling to test a conceptual model of HRQL in coronary artery disease. The model, which included biomedical factors and individual and environmental characteristics, was tested in a multicenter group of 465 patients at three timepoints ( baseline evaluation of chest pain and 1- and 3-month follow-ups). A satisfactory fit was obtained for the model over time. Depression and anxiety symptoms exerted the most significant influence on HRQL. HRQL and the mediating factors were found to be distinct phenomena. The authors concluded that mediating factors, especially depression and anxiety symptoms, should be taken into consideration in clinical routine if HRQL is regarded as a clinical outcome.