Gadolinium enhanced nuclear magnetic resonance images of experimental brain abscess.
Gadolinium enhanced nuclear magnetic resonance images of experimental brain abscess.
复制标题
钆增强实验性脑脓肿的核磁共振图像。
DOI：
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发表时间：
1984
影响因子：
1.3
通讯作者：
L. Bilaniuk
中科院分区：
文献类型：
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作者：
R. Grossman;G. Wolf;D. Biery;J. Mcgrath;H. Kundel;J. Aronchick;R. Zimmerman;H. Goldberg;L. Bilaniuk
钆-DTPA是一种顺磁性造影剂，以类似于泛影葡胺的方式分布在全身，对一只患有血源性诱导实验性颅内脓肿的猴静脉给药。立即进行对比增强计算机断层扫描（CT）和钆增强饱和恢复核磁共振（NMR），并在延迟30分钟后重复。核磁共振图像显示在CT显示结节时有明显的环形增强。两种成像模式进行了分析，相对于病理标本。钆-DTPA可能是一种有效的药物，用于成像改变的血脑屏障。
Gadolinium-DTPA, a paramagnetic contrast agent that distributes throughout the body in a manner similar to diatrizoate, was intravenously administered to a monkey with a hematogenously induced experimental intracranial abscess. Contrast enhanced computed tomography (CT) and gadolinium enhanced saturation-recovery nuclear magnetic resonance (NMR) were both performed immediately and repeated after a 30 min delay. The NMR images revealed marked ring enhancement at a time when CT showed a nodule. Both imaging modalities were analyzed with respect to the pathological specimen. Gadolinium-DTPA may be an effective agent for imaging alterations of the blood-brain barrier.