Gender differences in depression, but not in anxiety in people with epilepsy
Gender differences in depression, but not in anxiety in people with epilepsy
复制标题
DOI：
10.1016/j.seizure.2015.07.012
复制
发表时间：
2015-11-01
影响因子：
3
通讯作者：
Kendel, Friederike
中科院分区：
文献类型：
--
作者：
Gaus, Verena;Kiep, Henriette;Kendel, Friederike
目的：焦虑和抑郁是癫痫患者常见的共病，但可能的性别差异往往被忽视。本研究的目的是分析男性和女性癫痫患者在焦虑和抑郁症状方面是否存在差异，并确定可能的预测因素。（N = 302; 53%的女性）完成了自我报告问卷，包括患者健康问卷（PHQ-9）的抑郁模块，医院焦虑和抑郁量表（HADS-A）的焦虑模块和癫痫患者加权生活质量量表-31-P的“药物效应”和“癫痫发作担忧”分量表结果：焦虑程度没有性别差异（p = 0.532），这主要是由于男性的焦虑水平高于一般人群。抑郁症状的性别差异显著（p = 0.009），女性患者受影响更大。焦虑和抑郁症状的最重要的预测因素是药物的不利影响（QOL药物影响）和癫痫发作的担忧（QOL癫痫发作担忧）。此外，这些预测因素更密切相关的焦虑和抑郁症状的manes.Conclusion：未来的干预研究可以显示是否提供更多的信息，疾病和药物治疗的效果可能会改善焦虑和抑郁。我们的研究结果表明，这种干预措施应针对男性和女性的不同需求。(C)2015年英国癫痫协会。由爱思唯尔有限公司出版。保留所有权利。
Purpose: Anxiety and depression are frequent comorbidities in people with epilepsy (PWE), but possible gender differences are often neglected. The aim of the present study was to analyze if men and women with epilepsy differ with regard to anxiety and depressive symptoms and to identify possible predictors.Methods: Adult consecutive PWE (N = 302; 53% women) completed self-report questionnaires, including the depression module of the Patient Health Questionnaire (PHQ-9), the anxiety module of the Hospital Anxiety and Depression Scale (HADS-A) and the subscales "medication effects" and "seizure worry" of the Patient-weighted Quality of Life in Epilepsy Inventory-31-P (QOLIE-31-P).Results: There was no gender difference in extent of anxiety (p = .532), which was mainly due to higher anxiety levels in men compared to the general population. The gender difference in depressive symptoms was significant (p = .009), with female patients being more affected. The most important predictors for anxiety and depressive symptoms were detrimental effects of medication (QOL medication effects) and of seizure worry (QOL seizure worry). Moreover, these predictors were more closely associated with anxiety and depressive symptoms in men.Conclusion: Future intervention studies could show whether providing more information about the illness and medication effects may improve anxiety and depression. Our results suggest that such interventions should be tailored to the different needs of men and women. (C) 2015 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.