Paraneoplastic encephalitis associated with myasthenia gravis and malignant thymoma
Paraneoplastic encephalitis associated with myasthenia gravis and malignant thymoma
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DOI：
10.1016/j.jocn.2011.05.026
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发表时间：
2012-02-01
影响因子：
2
通讯作者：
Sobue, Gen
中科院分区：
文献类型：
--
作者：
Miyazaki, Yu;Hirayama, Masaaki;Sobue, Gen
我们提出了一个病人与B2型胸腺瘤（世界卫生组织胸腺瘤分类）的并发症，抗肌肉乙酰胆碱受体抗体阳性重症肌无力和抗电压门控钾通道抗体与副肿瘤性脑炎。在疾病期间观察到这些神经系统疾病发作与临床症状分离之间的时间差异。这份报告提醒临床医生，长期随访是必要的，患者有残留的胸腺瘤，并应注意其他伴随的自身免疫性疾病。(C)2011爱思唯尔有限公司保留所有权利。
We present a patient with type B2 thymoma (World Health Organization Thymoma Classification) with the complications of anti-muscle acetylcholine receptor antibody-positive myasthenia gravis and anti-voltage-gated potassium channel antibodies associated with paraneoplastic encephalitis. A timing difference between the onset of these neurological disorders and a dissociation of clinical symptoms was observed during the disease. This report alerts clinicians that long-term follow-up is needed where patients have a residual thymoma and attention should be paid to other concomitant autoimmune disorders. (C) 2011 Elsevier Ltd. All rights reserved.