PREVALENCE OF ATRIAL-FIBRILLATION IN ELDERLY SUBJECTS (THE CARDIOVASCULAR HEALTH STUDY)
PREVALENCE OF ATRIAL-FIBRILLATION IN ELDERLY SUBJECTS (THE CARDIOVASCULAR HEALTH STUDY)
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DOI：
10.1016/0002-9149(94)90363-8
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发表时间：
1994-08-01
影响因子：
2.8
通讯作者：
RAUTAHARJU, PM
中科院分区：
文献类型：
--
作者：
FURBERG, CD;PSATY, BM;RAUTAHARJU, PM
心房颤动（AF）是老年人常见的心律失常，也是栓塞性卒中的常见原因。大多数关于AF患病率和相关性的研究都使用了选定的医院人群。心血管健康研究是一项以人群为基础的纵向研究，研究了5，201名年龄大于或等于65岁的男性和女性的冠状动脉疾病和中风风险因素。在基线检查时，4.8%的女性和6.2%的男性被诊断为AF，并且患病率与女性的高龄密切相关。在有临床心血管疾病的男性和女性中，AF的患病率为9.1%，在有亚临床证据但无临床心血管疾病的患者中为4.6%，在既无临床心血管疾病也无亚临床心血管疾病的受试者中仅为1.6%。有充血性心力衰竭、心脏瓣膜病和卒中病史，超声心动图显示左心房尺寸增大，二尖瓣或主动脉瓣功能异常，经治疗的全身性高血压，和高龄与AF的患病率独立相关。在没有临床和亚临床心血管疾病的情况下，AF的低患病率使人们对如此-在老年人中被称为“孤立性心房颤动”。
Atrial fibrillation (AF) is a common arrhythmia in elderly persons and a common cause of embolic stroke. Most studies of the prevalence and correlates of AF have used selected, hospital-based populations. The Cardiovascular Health Study is a population-based, longitudinal study of risk factors for coronary artery disease and stroke in 5,201 men and women aged greater than or equal to 65 years. AF was diagnosed in 4.8% of women and in 6.2% of men at the baseline examination, and prevalence was strongly associated with advanced age in women. Prevalence of AF was 9.1% in men and women with clinical cardiovascular disease, 4.6% in patients with evidence of subclinical but no clinical cardiovascular disease, and only 1.6% in subjects with neither clinical nor subclinical cardiovascular disease. A history of congestive heart failure, valvular heart disease and stroke, echocardiographic evidence of enlarged left atrial dimension, abnormal mitral or aortic valve function, treated systemic hypertension, and advanced age were independently associated with the prevalence of AF. The low prevalence of AF in the absence of clinical and subclinical cardiovascular disease calls into question the existence and clinical usefulness of the concept of so-called ''lone atrial fibrillation'' in the elderly.