Gender differences in mental disorders and suicidality in Europe: Results from a large cross-sectional population-based study

Gender differences in mental disorders and suicidality in Europe: Results from a large cross-sectional population-based study
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DOI:
10.1016/j.jad.2014.11.002
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发表时间:
2015-03-01
影响因子:
6.6
通讯作者:
Kovess-Masfety, Vivane
Kovess-Masfety, Vivane
中科院分区:
医学2区
文献类型:
--
作者:
Boyd, Anders;Van de Velde, Sarah;Kovess-Masfety, Vivane

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简介:当评估性别差异的精神障碍和自杀,特别是欧洲国家之间,研究是稀疏的,经常阻碍了方法问题,如有限的项目评估和不一致的抽样designs.Methods:在十个欧洲国家参加世界精神卫生调查倡议,终身内化和外化障碍和自杀进行了评估,37,289名受访者。使用DMS-IV标准对疾病进行分类。优势比(OR)的性别差异进行了计算,而各年龄组的趋势进行了测试,通过性别x年龄interaction.Results:在国家内,任何终身内化障碍的患病率范围从10.8%至44.5%之间的妇女和5.9%至26.5%之间的男子,与妇女一贯高于男性的优势比(OR范围:1.52-2.73)。任何终生外化障碍的患病率在vvomen中为02%至6.6%,在男性中为2.2%至22.4%,女性的几率始终低于男性(OR范围:0.05-0.35)。在0.8-5.4%的女性和0.3-2.4%的男性中发现了任何终身自杀企图,显示出各国之间不一致的相对性别差异(OR范围:0.77-4.72)。在法国(p=0.01)、荷兰(p=0.05)和西班牙(p = 0.02),没有观察到任何内化障碍或自杀企图对性别或年龄组的显著影响,但任何外化障碍都存在vvere。自杀并不完全代表更重要的临床事件,如自杀mortality.Conclusions:在欧洲国家一致,内化障碍是更常见的女性和男性之间的外化障碍,而自杀的性别差异各不相同。(C)2014 Elsevier B. V.保留所有权利。
Introduction: When evaluating gender differences in mental disorders and suicidality, specifically between European countries, studies are sparse and frequently hindered by methodological issues, such as the limited items evaluated and inconsistent sampling designs.Methods: In ten European countries participating in the World Mental Health Survey Initiative, lifetime internalizing and externalizing disorders and suicidality were assessed among 37,289 respondents. Disorders were classified using DMS-IV criteria. Odds ratios (OR) for gender differences were calculated using logistic regression, while trends across age groups were tested via gender x age interaction.Results: Within countries, prevalence of any lifetime internalizing disorder ranged from 10.8% to 44.5% among women and 5.9% to 26.5% among men, with women having consistently higher odds than men (OR range: 1.52-2.73). Prevalence of any lifetime externalizing disorders ranged from 02% to 6.6% among vvomen and 2.2% to 22.4% among men, with women having consistently lower odds than men (OR range: 0.05-0.35). Any lifetime suicide attempt was found in 0.8-5.4% of women and 0.3-2.4% of men, showing inconsistent relative gender differences across countries (OR range: 0.77-4.72). Significant effects in gender OR across age groups were not observed for any internalizing disorder or suicide attempt, yet vvere present for any externalizing disorder in France (p=0.01), the Netherlands (p=0.05), and Spain (p = 0.02).Limitations: Mental disorders were assessed with the CIDI 3.0 and not psychiatric evaluations. Suicidality does not fully represent more important clinical events, such as suicide mortality.Conclusions: Consistent across European countries, internalizing disorders are more Common among women and externalizing disorders among men, whereas gender differences in suicidality varied. (C)2014 Elsevier B.V. All rights reserved.