Quantitative analysis of chemical constituents in different commercial parts of Notopterygium incisum by HPLC-DAD-MS
Quantitative analysis of chemical constituents in different commercial parts of Notopterygium incisum by HPLC-DAD-MS
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DOI：
10.1016/j.jep.2009.09.011
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发表时间：
2009-12-10
影响因子：
5.4
通讯作者：
Ding, Lisheng S.
中科院分区：
文献类型：
--
作者：
Liu, Xin;Jiang, Shunyuan;Ding, Lisheng S.
民族药理学相关性：钩唐作为抗风湿镇痛药，治疗风湿、头痛、感冒等。研究目的：为了更有效地利用钩唐，本研究对钩唐不同市售部位及纤维根的主要化学成分进行了分析。材料与方法：本研究所用的切牙无毛菌标本均采自中国四川省。采用HPLC-DAD-MS定量分析了切牙白杨不同商品部位及纤维根的主要化学成分。结果：根据不同的商品部位，对2个主要产区的10份切齿nottoteryum样品进行了调查，并对4种主要成分进行了定量分析。结论：根状茎质量优于主根。出乎意料的是，白杨纤维根中两种主要成分——诺托特酚和异欧维芹素的含量高于切牙白杨的其他部位。这一结果暗示了纤维根也可能有价值，我们应该对其进行研究，以发掘其潜力。2009爱思唯尔爱尔兰有限公司版权所有。
Ethnopharmacological relevance: Notopterygium incisum used as an antirheumatic and analgesic medicine for the treatment of rheumatism, headache, cold, etc., is not only a traditional Qiang medicine, but also a traditional Tibetan remedy for thousands of years.Aim of the study: In order to use this herbal medicine in a more effective way, in the present investigation, we analyzed the main chemical constituents of different commercial parts as well as fibrous roots of Notopterygium incisum.Materials and methods: All crude Notopterygium incisum samples used in this study were collected in Sichuan province of China. We used HPLC-DAD-MS to analyze quantitatively the main chemical constituents of different commercial parts as well as fibrous roots of Notopterygium incisum.Results: According to different commercial parts, 10 Notopterygium incisum samples collected from two main production areas have been investigated, and four main constituents have been quantitatively analyzed.Conclusion: The quality of rhizomes is better than that of main roots. Unexpectedly, the content of two main constituents, notopterol and isoimperaorin, in fibrous roots is higher than any other parts of Notopterygium incisum. This result implied that the fibrous root may also have value, and we should study it to explore its potential. (C) 2009 Elsevier Ireland Ltd. All rights reserved.