Candida glabrata, an emerging fungal pathogen, exhibits superior relative cell surface hydrophobicity and adhesion to denture acrylic surfaces compared with Candida albicans
Candida glabrata, an emerging fungal pathogen, exhibits superior relative cell surface hydrophobicity and adhesion to denture acrylic surfaces compared with Candida albicans
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DOI：
10.1034/j.1600-0463.2002.1100902.x
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发表时间：
2002-09-01
期刊：
影响因子：
2.8
通讯作者：
Samaranayake, LP
中科院分区：
文献类型：
--
作者：
Luo, G;Samaranayake, LP
口腔念珠菌病是虚弱个体中常见的机会性感染，光滑念珠菌是仅次于白色念珠菌的第二常见分离种。念珠菌对各种生物或非生物表面的黏附被认为是念珠菌感染定植和发病的先决条件，其相对细胞表面疏水性(CSH)可能是参与这一过程的一种可能的力量。虽然关于白色念珠菌的后一种特征的大量数据是可用的，但令人惊讶的是，关于光滑念珠菌的信息很少。作为念珠菌相对粘附性和CSH的综合数据库。对34株口腔光滑念珠菌和15株白色念珠菌的体外药敏特性进行了研究。光肩星天牛的CSH和粘附力均存在显著的种内差异(P
Oral candidosis is a common opportunistic infection in debilitated individuals and Candida glabrata is the second most frequently isolated species from this condition, after Candida albicans. Candidal adherence to various biological or non-biological surfaces is considered a prerequisite for colonization, and pathogenesis of candidal infections, and their relative cell surface hydrophobicity (CSH) is likely to be a possible contributory force involved in this process. Whereas a large body of data on the latter features of C albicans is available, there is surprisingly little information on C glabrata. As a comprehensive database on the relative adhesion and CSH of Candida spp. is instructive and useful, we investigated in vitro the latter attributes of 34 oral isolates of C glabrata and 15 isolates of C albicans. There were remarkable intraspecies differences in both the CSH and the adhesive ability of C glabrata strains (p