FECAL SHORT-CHAIN FATTY-ACIDS IN BREAST-FED AND FORMULA-FED BABIES
FECAL SHORT-CHAIN FATTY-ACIDS IN BREAST-FED AND FORMULA-FED BABIES
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DOI：
10.1111/j.1651-2227.1994.tb13059.x
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发表时间：
1994-05-01
期刊：
影响因子：
3.8
通讯作者：
WHARTON, BA
中科院分区：
文献类型：
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作者：
EDWARDS, CA;PARRETT, AM;WHARTON, BA
母乳喂养的婴儿肠道菌群不同于配方奶粉喂养的婴儿。据认为，这种菌群的差异可能是母乳喂养的婴儿较少患胃肠道疾病的一个重要原因。肠道菌群的差异反映在粪便短链脂肪酸（SCFA）的分布上。对于母乳喂养或婴儿配方奶粉喂养的婴儿粪便中SCFA的浓度知之甚少。在这项研究中，研究人员对两周和四周大的婴儿进行了粪便中短链脂肪酸的测量，这些婴儿要么是纯母乳喂养，要么是从出生起就用奶瓶喂养。当包括乳酸时，母乳喂养和配方奶喂养的婴儿的总粪便SCFA浓度没有显著差异。然而，与母乳喂养的婴儿相比，配方奶喂养的婴儿乳酸较少，丙酸和正丁酸浓度较高。很少有婴儿有显著水平的正丁酸，尽管这种SCFA被认为对成人结肠黏膜的健康很重要。
The intestinal flora of breast-fed infants differs from that of formula-fed infants. It is thought that this difference in flora may be one important reason why breast-fed babies suffer less from gastrointestinal disease. Differences in intestinal flora are reflected in the profile of faecal short chain fatty acids (SCFA). Very little is known about faecal concentrations of SCFA in babies fed breast milk or infant formula. In this study, faecal SCFA were measured in babies at two and four weeks of age who had been either exclusively breast fed or bottle fed from birth. There was no significant difference in total faecal SCFA concentrations between breast-fed and formula-fed babies when lactate was included. The formula-fed group, however, had less lactic acid and higher concentrations of propionic and n-buytric acids than breast-fed babies. Very few babies had significant levels of n-butyric acid, although this SCFA is believed to be important for the health of the colonic mucosa of adults.