Quantitative ultrasound parametric images of cancellous bone compared to X-ray computed tomography
Quantitative ultrasound parametric images of cancellous bone compared to X-ray computed tomography
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松质骨的定量超声参数图像与 X 射线计算机断层扫描的比较
DOI：
10.1109/ultsym.1994.401870
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
G. Berger
中科院分区：
文献类型：
--
作者：
P. Laugier;K. Beldjelti;P. Droin;P. Giat;G. Berger
定量超声是一种无辐射技术，能够评估 X 射线吸收测定法或定量计算机断层扫描等其他测量无法反映的骨骼特性。我们之前已经证明，超声速度和衰减的定量图像是表征跟骨等异质介质的精确方法。本研究将超声波特性图像与从尸体上取出的 15 个跟骨（年龄从 69 岁到 89 岁）的 X 射线计算机断层扫描 (CT) 图像进行了比较。速度、衰减和骨矿物质密度 (BMD) 的值在感兴趣区域 (ROI) 上进行平均，这些区域与三幅图像完全匹配。衰减与速度的相关系数为r=0.98，衰减与BMD的相关系数为r=0.43，速度与BMD的相关系数为r=0.91。观察到的超声和 QCT 之间的相关系数非常显着 (p<10 -4)，但 BMD 变化无法解释超声参数的大约 15% 至 20% 的变异性。该技术还产生了骨骼的弹性图像。通过结合超声波扫描测量样品中的局部声速和 X 射线计算机断层扫描测量其局部质量密度来获得弹性图像。弹性映射可能有助于使用有限元对骨骼的弹性行为进行建模以及计算局部应力和整体变形
Quantitative ultrasound is a radiation free technique able to assess skeletal properties that may not be reflected by other measurements like X-ray absorptiometry or quantitative computed tomography. We have previously shown that quantitative images of ultrasound velocity and attenuation is a precise method to characterize a heterogeneous medium such as the calcaneus. The present study compares the images of ultrasonic properties with the X-ray computed tomography (CT) images from 15 calcanei removed from cadavers (age ranging from 69 to 89). The values of velocity, attenuation and bone mineral density (BMD) were averaged over regions of interest (ROI) which were exactly matched for the three images. The correlation coefficient between attenuation and velocity was r=0.98, between attenuation and BMD r=0.43 and between velocity and BMD r=0.91. The observed correlation coefficients between ultrasound and QCT were highly significant (p<10 -4), but it leaves about 15% to 20% of the variability of ultrasound parameters unexplained by the BMD variation. The technique also yielded elasticity images of bone. Elasticity images were obtained by combining ultrasonic scanning measurement of the local velocity of sound in the sample with X-ray computed tomographic measurement of its local mass density. Elasticity mapping might be useful for modelling with finite elements the elastic behaviour of bone and to compute local stresses and overall deformations