Pertussis vaccination in infancy and asthma or allergy in later childhood: birth cohort study
Pertussis vaccination in infancy and asthma or allergy in later childhood: birth cohort study
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DOI：
10.1136/bmj.38045.858889.eb
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发表时间：
2004-04-17
影响因子：
--
通讯作者：
Henderson, J
中科院分区：
文献类型：
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作者：
Maitra, A;Sherriff, A;Henderson, J
一些研究表明，婴儿接种全细胞灭活百日咳疫苗与哮喘和特应性疾病的后期发展之间存在联系。1 2一项随机对照试验不同意这些结果，但只进行了30个月的随访。3我们之前关于百日咳疫苗接种和喘息障碍之间没有关联的报告是基于儿童早期的结果。4在这项研究中，我们在一个基于人群的大型出生队列中，研究了婴儿时期接种百日咳疫苗与7.5岁前哮喘或特应性疾病之间的关系。
Some studies have shown a link between vaccination of infants with whole cell inactivated pertussis vaccine and the later development of asthma and atopy. 1 2 A randomised controlled trial disagreed with these findings, but follow up was done until only 30 months of age. 3 Our previous report of the lack of an association between pertussis vaccination and wheezing disorders was based on outcomes in early childhood. 4 In this study we have examined the association between pertussis vaccination in infancy and asthma or atopy by age 7.5 years in a large, population based birth cohort.