Effect of chronic corticosteroid administration on diaphyseal and metaphyseal bone mass.
Effect of chronic corticosteroid administration on diaphyseal and metaphyseal bone mass.
复制标题
长期皮质类固醇给药对骨干和干骺端骨量的影响。
DOI：
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发表时间：
1974
影响因子：
5.8
通讯作者：
L. Avioli
中科院分区：
文献类型：
--
作者：
T. Hahn;V. Boisseau;L. Avioli
ABSTRACT Bone mass was measured by the photon absorption technique in the forearm of 490 normals, 36 patients with idiopathic osteoporosis, 21 patients with rheumatoid arthritis who had not received corticosteroid therapy, 48 patients who had been maintained on corticosteroid therapy for one or more years, 2 patients with Cushing's disease and 25 patients with primary hyperparathyroidism. Measurements were made at two points along the radius, a proximal diaphyseal site which is comprised primarily of cortical bone (DM) and a distal metaphyseal site reflecting a greater proportion of trabecular bone (MM). Patients with idiopathic osteoporosis and rheumatoid arthritis not treated with steroids both showed a parallel percentage loss of bone mass at the DM and MM sites, a pattern similar to the pattern of bone loss seen in normal subjects with aging. In contrast, patients with primary hyperparathyroidism and corticosteroid-induced osteopenia both showed a significantly greater degree of loss at the MM site. T...
