The expression of 5T4 antigen in colorectal and gastric carcinoma.
The expression of 5T4 antigen in colorectal and gastric carcinoma.
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DOI：
10.1038/bjc.1992.375
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发表时间：
1992-11
影响因子：
8.8
通讯作者：
Stern, P L
中科院分区：
文献类型：
--
作者：
Starzynska, T;Rahi, V;Stern, P L
应用免疫组织化学技术，检测72例结直肠癌和27例胃癌冰冻切片中癌滋养细胞表面抗原5T4的表达。恶性细胞中5T4的表达与肿瘤的转移转移密切相关。结果表明，癌细胞中5T4分子的出现反映了一种改变，这可能有助于转移潜能的发展。
The expression of 5T4, an oncotrophoblast cell surface antigen was examined in 72 colorectal and 27 gastric carcinomas, with immunoperoxidase technique, on frozen sections. Highly significant association was found between 5T4 expression in the malignant cells and metastatic spread. The results suggest that the appearance of 5T4 molecules in cancer cells reflects a change which may contribute to the development of metastatic potential.