Spontaneous regression of nonfunctioning pituitary macroadenoma: A case report
Spontaneous regression of nonfunctioning pituitary macroadenoma: A case report
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无功能性垂体大腺瘤自发消退：一例报告
DOI：
10.1016/j.inat.2016.06.003
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
J. Kuratsu
中科院分区：
文献类型：
--
作者：
Koki Kameno;S. Yano;N. Shinojima;J. Kuratsu
一个案件涉及一个13岁的女孩与无功能垂体大腺瘤进行了讨论。患者在发生继发于晕厥的头部损伤后前往医院进行检查。计算机断层扫描（CT）显示垂体肿块密度轻度增高。磁共振成像（MRI）与对比增强显示，肿块包含一个高信号区，它提出了视交叉。患者右眼视力模糊。内分泌检查未见异常，一个月后病人入院接受手术切除肿块，视力有改善。重复MRI显示垂体肿块的大小急剧减小。在接下来的2年中，肿块显示尺寸进一步减小，并且没有重新生长。由于未观察到垂体卒中的症状，我们认为首次就诊时发生的无症状卒中可能导致肿瘤消退。
A case involving a 13-year-old girl with nonfunctioning pituitary macroadenoma is discussed. The patient visited the hospital for checkup after experiencing a head injury secondary to syncope. A computed tomography (CT) scan revealed a pituitary mass with mildly higher density. Magnetic resonance imaging (MRI) with contrast enhancement showed that the mass contained a hyperintense area and it elevated the optic chiasm. The patient had blurred vision in her right eye. No endocrinological abnormalities were found. When the patient was admitted for surgical removal of the mass 1 month later, her visual acuity had improved. A repeat MRI showed that the size of the pituitary mass had dramatically reduced. During the following 2 years, the mass showed further reduction in size and did not re-grow. Since symptoms of pituitary apoplexy were not observed, we believe that asymptomatic apoplexy occurring at the time of the first visit may have caused regression of the tumor.