Intranasal volume and olfactory function
Intranasal volume and olfactory function
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DOI：
10.1093/chemse/27.9.831
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发表时间：
2002-11-01
期刊：
影响因子：
3.5
通讯作者：
Hummel, T
中科院分区：
文献类型：
--
作者：
Damm, M;Vent, J;Hummel, T
这项探索性研究的目的是确定鼻腔内的体积，因为它们与嗅觉功能参数有关。健康男性志愿者50例，年龄22~59岁，平均28.5岁。通过偏侧化苯乙醇气味阈值和气味辨别以及双侧气味辨别来测量嗅觉功能。嗅觉测量后立即进行鼻腔磁共振成像。为了将嗅觉测量结果与鼻腔体积相关联，将每个鼻腔分为11个部分。嗅觉阈值与右鼻腔上、下鼻道前部的体积呈显著正相关。这些结果表明，健康人嗅觉阈值个体间差异的两个鼻段是重要的：(I)筛板以下的上鼻道段和(Ii)下鼻道的前段。后一种发现对鼻外科特别有意义，它允许通过切除下鼻甲和/或鼻中隔成形术来改变这一体积。
The aim of this exploratory study was to identify the volume intranasal segments as they relate to parameters of olfactory function. Fifty healthy male volunteers (age range 22-59 years, mean age 28.5 years) were included. Olfactory function was measured by lateralized phenyl ethyl alcohol odor thresholds and odor discrimination, and by bilateral odor identification. Magnetic resonance imaging of the nasal cavity was performed immediately following olfactometry. To correlate the results of olfactometry with intranasal volume, each nasal cavity was divided into 11 segments. Significant correlations were found between the odor thresholds and volumes of the anterior part of the lower and upper meatus of the right nasal cavity. These results reveal that two nasal segments are important for inter-individual differences of odor thresholds in healthy subjects: (i) the segment in the upper meatus below the cribriform plate and (ii) the anterior segment of the inferior meatus. The latter finding is of special interest for nasal surgery, which allows modification of this volume through resection of the inferior turbinate and/or septoplasty.