Daytime sleepiness and cognitive impairment in the elderly population
Daytime sleepiness and cognitive impairment in the elderly population
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DOI：
10.1001/archinte.162.2.201
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发表时间：
2002-01-28
影响因子：
--
通讯作者：
Vecchierini, MF
中科院分区：
文献类型：
--
作者：
Ohayon, MM;Vecchierini, MF
背景：最近的研究结果表明，白天过度嗜睡（ENDS）与认知缺陷之间可能存在关系。本研究旨在确定EDS在多大程度上预测老年人的认知障碍。方法：采用Sleep-EVAL专家系统对居住在法国巴黎大都市区、具有代表性的60岁及以上普通人群1026例进行电话访谈。为了找到这些个体，我们随机抽取了7010个家庭，其中1269个家庭中至少有1名家庭成员在这个年龄段（参与率为80.9%）。除了第四版《精神障碍诊断与统计手册》和《国际睡眠障碍诊断分类》之外，该系统还对参与者进行了心理一般健康量表、认知困难量表（MacNair-R）和独立生活量表。结果：13.6%的样本报告白天过度嗜睡，年龄组之间无显著差异。与不睡觉的参与者相比，在控制了年龄、性别、体育活动、职业、有机疾病、使用睡眠或焦虑药物、睡眠持续时间和心理健康之后，EDS患者在MacNair-R量表的所有维度上都有更高的认知障碍风险。注意-集中缺陷的奇比为2.1，实践的为1.7，延迟回忆的为2.0，人定向困难的为2.5，时间定向困难的为2.2，前瞻记忆的为1.8。结论：在普通人群中的老年人中，EDS是认知功能障碍的重要危险因素。表明潜在认知障碍的可能性，需要评估。
Background: Recent findings suggest that there may be a relationship between excessive daytime sleepiness (ENDS) and cognitive deficits. This study aims to determine to what extent EDS is predictive of cognitive impairment in an elderly population.Methods: A total of 1026 individuals 60 years or older representative of the general population living in the metropolitan area of Paris, France, were interviewed by telephone using the Sleep-EVAL expert system. To find these individuals, 70 10 randomly selected households were called: 1269 had at least I household member in this age range (participation rate, 80.9%). In addition to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and International Classification of Sleep Disorders diagnoses, the system administered to participants the Psychological General Well-being Schedule, the Cognitive Difficulties Scale (MacNair-R), and an independent living scale.Results: Excessive daytime sleepiness was reported by 13.6% of the sample, with no significant difference among age groups. Compared with nonsleepy participants, those, with EDS were at increased risk of cognitive impairment on all the dimensions of the MacNair-R scale after controlling for age, sex, physical activity, occupation, organic diseases, use, of sleep or anxiety medication, sleep duration, and psychological wellbeing. The odd ratios were 2.1 for attention-concentration deficits, 1.7 for praxis, 2.0 for delayed recall, 2.5 for difficulties in orientation for persons, 2.2 for difficulties in temporal orientation, and 1.8 for prospective memory.Conclusions: Among elderly individuals in the general population, EDS is an important risk factor for cognitive impairment, A complaint of EDS by an elderly patient should. signal the possibility of an underlying cognitive impairment in need of evaluation.