Sphaerialactonam, a γ-lactam-isochromanone from the Hawaiian endophytic fungus Paraphaeosphaeria sp FT462
Sphaerialactonam, a γ-lactam-isochromanone from the Hawaiian endophytic fungus Paraphaeosphaeria sp FT462
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DOI:
10.1016/j.tetlet.2017.02.052
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发表时间:
2017-03-29
影响因子:
1.8
通讯作者:
Cao, Shugeng
中科院分区:
文献类型:
--
作者:
Huang, Peng;Li, Chunshun;Cao, Shugeng
Reinvestigation of the endophytic fungus Paraphaeosphaeria sp. FT462 from the Hawaiian plant Lycopodiella cernua (L) Pic. Serm led to the isolation and identification of a unique gamma-lactamisochromanone (1). The structure of 1 was determined by NMR, MS spectroscopic analysis, and quantum chemical calculations of NMR. The compound was tested inactive against A2780 and A2780cisR. (C) 2017 Elsevier Ltd. All rights reserved.