Development of Pr:LuAG Scintillator Array and Assembly for Positron Emission Mammography
Development of Pr:LuAG Scintillator Array and Assembly for Positron Emission Mammography
复制标题
DOI：
10.1109/tns.2009.2032265
复制
发表时间：
2010-06
影响因子：
1.8
通讯作者：
T. Yanagida;A. Yoshikawa;Y. Yokota;K. Kamada;Y. Usuki;S. Yamamoto;M. Miyake;M. Baba;Kazuaki Kumagai;Katsuhisa Sasaki;Masatoshi Ito;Naoto Abe;Y. Fujimoto;S. Maeo;Y. Furuya;Hidehiko Tanaka;A. Fukabori;Targino Rodrigues dos Santos;M. Takeda;N. Ohuchi
中科院分区：
文献类型：
--
作者：
T. Yanagida;A. Yoshikawa;Y. Yokota;K. Kamada;Y. Usuki;S. Yamamoto;M. Miyake;M. Baba;Kazuaki Kumagai;Katsuhisa Sasaki;Masatoshi Ito;Naoto Abe;Y. Fujimoto;S. Maeo;Y. Furuya;Hidehiko Tanaka;A. Fukabori;Targino Rodrigues dos Santos;M. Takeda;N. Ohuchi
摘要/ abstract摘要：为了更高效的早期发现乳腺癌，我们打算利用Pr:LuAG单晶作为该扫描仪的闪烁体，开发正电子发射乳房x线摄影（PEM）。PEM具有与PET相同的机制，在PET两侧的两台伽玛相机检测到两条511 keV湮灭伽马射线，并对数据进行重建，显示出具有恶性分级的肿瘤位置。每个晶体经过切割和抛光加工后，物理尺寸为2.1 × 2.1 × 15 mm3，使用覆盖BaSO4反射镜的Pr:LuAG阵列作为传感器头。一个相机单元由20 × 64像素光学耦合三个H8500-03多阳极pmt组成。我们的PEM每侧需要四个摄像头。最后，在样机两侧安装了8个摄像头，并利用乳房幻影中的18F来评估空间分辨率。
Abstract-In order to detect the breast cancer at the early stage with high efficiency, we intend to develop positron emission mammography (PEM), using Pr:LuAG single crystal as a scintillator of this scanner. PEM has the same mechanism of PET, where two 511 keV annihilation gamma-rays are detected by two gamma cameras at opposite side, and reconstruction of the data shows the position of the cancer with malignancy grades. After cutting and polishing processes for each crystal to a physical dimensions of 2.1 × 2.1 × 15 mm3, Pr:LuAG array covered with BaSO4 reflector was used as a sensor head. The one camera unit consisted of 20 × 64 pixels optically coupled with three H8500-03 multi anode PMTs. Our PEM required four cameras at each side. Finally, eight cameras were installed in both sides of the prototype instrument and the spatial resolution was evaluated using the 18F in the breast phantom.