A novel water soluble multifunctional fluorescent probe for highly sensitive and ultrafast detection of anionic surfactants and wash free imaging of Gram-positive bacteria strains
A novel water soluble multifunctional fluorescent probe for highly sensitive and ultrafast detection of anionic surfactants and wash free imaging of Gram-positive bacteria strains
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一种新型水溶性多功能荧光探针，用于高灵敏、超快速检测阴离子表面活性剂以及革兰氏阳性细菌菌株的免洗成像
DOI：
10.1016/j.dyepig.2017.05.006
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发表时间：
2017-08-01
影响因子：
4.5
通讯作者：
Zeng, Wenbin
中科院分区：
文献类型：
--
作者：
Gao, Tang;Cao, Xiaozheng;Zeng, Wenbin
阴离子表面活性剂广泛应用于洗涤剂、化妆品、医药等行业，但残留在水中会污染水质，破坏水生生态系统。因此，开发一种快速、灵敏、选择性的阴离子表面活性剂检测策略具有重要意义。在此，我们基于聚集诱导发射（AlE）合理设计并合成了一种具有优异特性的新型荧光染料TPIM-ClO4。 TPIM-ClO4表现出许多无可比拟的特性，包括大斯托克斯位移（225 nm）、长波长发射（650 nm）、优异的水溶性和稳定性。它被证明是检测十二烷基硫酸钠的优秀探针，具有快速响应（40 s）、良好的选择性和极低的检测限48 nM（13.07 a），这归因于基于协同静电和疏水相互作用原位形成紧密堆积的纳米聚集体。 TPIM-ClO4进一步成功用于实际水样中十二烷基硫酸钠的检测，结果令人满意。此外，探针TPIM-ClO4还成功应用于革兰氏阳性菌的特异性荧光成像，无需洗涤步骤。这项研究可能为设计用于环境监测和微生物分析应用的基于AIE的荧光探针提供新策略。 (C) 2017 Elsevier Ltd. 保留所有权利。
Anionic surfactants are widely used in detergents, cosmetics, medicine and other industries, but the residue in the water can pollute the water quality and destruct aquatic ecosystems. Thus, to develop a rapid, sensitive and selective strategy for detection of anionic surfactants is of great importance. Herein, we rationally designed and synthesized a novel fluorescent dye TPIM-ClO4 with excellent characters based on aggregation-induced emission (AlE). TPIM-ClO4 exhibited many incomparable characteristics including large Stokes shifts (225 nm), long wavelength emission (650 nm), excellent water solubility and stability. It was demonstrated to be excellent probe for detection of sodium dodecyl sulfate with fast responding (40 s), good selectivity and extremely low detection limit 48 nM (13.07 a), which ascribe to the formation of tightly packed nanoaggregates in situ based on synergistic electrostatic and hydrophobic interactions. TPIM-ClO4 was further successfully used to the detection of sodium dodecyl sulfate in real water samples with satisfactory results. Furthermore, probe TPIM-ClO4 was also successfully applied for specific fluorescent imaging of Gram-positive bacteria without washing steps. This study may provide new strategy in designing AIE-based fluorescent probe for environmental monitoring and microbial analysis application. (C) 2017 Elsevier Ltd. All rights reserved.