Dynamic Light Scattering Studies of Biopolymers: Effects of Charge, Shape, and Flexibility
Dynamic Light Scattering Studies of Biopolymers: Effects of Charge, Shape, and Flexibility
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生物聚合物的动态光散射研究：电荷、形状和柔韧性的影响
DOI：
10.1146/annurev.pc.37.100186.001415
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发表时间：
1986
影响因子：
14.7
通讯作者：
K. Schmitz
中科院分区：
文献类型：
--
作者：
J. M. Schurr;K. Schmitz
Natural and synthetic biopolymers exhibit as many as three characteristic physical properties: namely, a large electric charge, a highly extended anisometric shape, and intermediate bending and twisting rigidities. In particular cases, each of these properties profoundly affects the trans lational and/or rotational Brownian dynamics over distance-and time scales that are accessible by dynamic light scattering (DLS) and related optical techniques. A principal challenge in this area is to understand how direct interactions, such as electrostatic forces or elastic restoring forces, between diffusing elements affect their Brownian dynamics. A related objective is to understand how the characteristic properties influence both intra-and intermolecular structures in solution. Biopolymers may also engage in electrostatic, cooperative, or other kinds of association equi libria, and may undergo conformational isomerizations, all of which may be sensitively manifested in their Brownian dynamics. Here the objective is often simply to identify and characterize these phenomena, some of
