Vitamin D in the treatment of pulmonary tuberculosis
Vitamin D in the treatment of pulmonary tuberculosis
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DOI：
10.1016/j.jsbmb.2006.12.052
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发表时间：
2007-03-01
影响因子：
4.1
通讯作者：
Griffiths, Christopher J.
中科院分区：
文献类型：
--
作者：
Martineau, Adrian R.;Honecker, Friedemann U.;Griffiths, Christopher J.
维生素D在前抗生素时代被用于治疗结核病。对10，25-二羟维生素D免疫调节特性的新认识重新点燃了维生素D作为抗结核治疗辅助剂的兴趣。我们描述了历史上使用的维生素D在结核病治疗：讨论的机制，它可能会调节宿主对结核分枝杆菌感染的反应，并审查三个临床试验和10个病例系列中，维生素D已被用于治疗肺结核。(c)2006爱思唯尔有限公司保留所有权利。
Vitamin D was used to treat tuberculosis in the pre-antibiotic era. New insights into the immunomodulatory properties of 10,25-dihydroxyvitamin D have rekindled interest in vitamin D as an adjunct to antituberculous therapy. We describe the historical use of vitamin D in tuberculosis treatment: discuss the mechanisms by which it may modulate host response to infection with Mycobacterium tuberculosis; and review three clinical trials and ten case series in which vitamin D has been used in the treatment of pulmonary tuberculosis. (c) 2006 Elsevier Ltd. All rights reserved.