Cohort Profile of the NEIGE Study in Tokamachi City, Japan
Cohort Profile of the NEIGE Study in Tokamachi City, Japan
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DOI：
10.2188/jea.je20190036
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发表时间：
2020-07-01
影响因子：
4.7
通讯作者：
Inoue, Shigeru
中科院分区：
文献类型：
--
作者：
Shobugawa, Yugo;Murayama, Hiroshi;Inoue, Shigeru
背景：研究表明，农村居民在医疗获取和社会经济条件方面面临劣势。然而，农村地区老年人健康的社会决定因素仍不清楚。神经元对跨代环境影响 (NEIGE) 研究调查了农村老年人健康的社会决定因素。方法：对日本十日町市的老年居民进行了一项调查。我们根据年龄（65-74 岁和 75-84 岁）和居住区域（十日町中心[市中心]和松野山[山区]）从四个分层组中随机选择研究参与者（N = 1,346）。该调查收集了有关社会经济状况、生活方式、健康和邻里环境的数据，还进行了血液和尿液采样。并评估身体活动。分析中还检查了磁共振脑成像（MRI）和Apo-E基因。结果：共有527人参与了NEIGE研究（参与率：39.2%）。参与者的平均年龄为 735（标准差，5.6）岁，其中 47.3% 为男性。市中心和山区居民之间的人口统计数据没有差异，但山区居民的受教育程度较低。生活方式相似，只是山区每天饮酒的比例较高（33.3-35.3%）。在身体健康方面，山区居民的肌肉质量、握力和身体活动量明显更高。然而，市中心居民的步态速度和平衡性更好。结论：NEIGE 研究的结果将有助于阐明日本农村老年人健康的社会决定因素，并强调市中心和山区之间的不同结果。
Background: Studies have shown that rural residents face disadvantages concerning medical access and socio-economic conditions. However, the social determinants of health among older people in rural areas are still unclear. The Neuron to Environmental Impact across Generations (NEIGE) study investigated the social determinants of health among older rural adults.Methods: A survey was conducted among the older residents of Tokamachi City, Japan. We randomly selected study participants (N = 1,346) from four stratified groups by age (65-74 and 75-84 years) and residential area (Tokamachi center [downtown] and Matsunoyama [mountain]). The survey collected data on socio-economic status, lifestyle, health, and neighborhood environment, Blood and urine sampling were also conducted. and physical activity was assessed. Magnetic resonance brain imaging (MRI) and Apo-E gene were also examined in the analysis.Results: In total, 527 people participated in the NEIGE study (participation rate: 39.2%). The average age of the participants was 735 (standard deviation, 5.6) years, and 47.3% were male. No differences in demographics were found between downtown and mountain residents, except for educational attainment, which was lower among mountain residents. Lifestyles were similar, except for the higher percentage of everyday drinkers (33.3-35.3%) in the mountain area. Concerning physical health, muscle mass, grip strength, and measured physical activity were significantly higher among mountain residents. However, gait speed and balance were better among downtown residents.Conclusion: The findings of the NEIGE study will help elucidate the social determinants of health in older rural adults in Japan, and emphasize the different outcomes between downtown and mountain areas.