Seroepidemiology of Entamoeba histolytica Infection in General Population in Rural Durango, Mexico.
Seroepidemiology of Entamoeba histolytica Infection in General Population in Rural Durango, Mexico.
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DOI：
10.14740/jocmr2131w
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发表时间：
2015-06-01
期刊：
影响因子：
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通讯作者：
Sanchez-Anguiano, Luis Francisco
中科院分区：
文献类型：
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作者：
Alvarado-Esquivel, Cosme;Hernandez-Tinoco, Jesus;Sanchez-Anguiano, Luis Francisco
背景：墨西哥溶组织内阿米巴的血清流行病学研究很少。该研究的目的是确定在杜兰戈，墨西哥农村地区成人溶组织芽胞杆菌抗体的血清患病率和相关因素。方法：通过一项横断面研究，用酶联免疫分析法测定了墨西哥杜兰戈农村282名成年人的溶组织芽胞杆菌IgG抗体。此外，还调查了血清阳性率与社会人口统计学、住房条件和研究对象的行为特征之间的关系。结果：282名农村被试中有118人（41.8%）有e抗体。溶组织IgG抗体。多因素分析显示，溶组织杆菌暴露与饮用水源呈正相关（OR = 2.73; 95% CI: 1.33 ~ 5.58; P = 0.005），与户主受教育程度低呈正相关（OR = 1.53; 95% CI: 1.03 ~ 2.27; P = 0.03）。相比之下，溶组织杆菌暴露与食用未经高温消毒的牛奶呈负相关（OR = 0.55; 95% CI: 0.31 - 0.96; P = 0.03），以及家中拥挤（OR = 0.33; 95% CI: 0.17 - 0.64; P = 0.0009）。结论：杜兰戈农村成人溶组织芽胞杆菌感染的血清患病率高于墨西哥其他人群。本研究中发现的溶组织芽胞杆菌血清阳性的相关因素可能有助于制定针对溶组织芽胞杆菌感染的最佳预防措施。
BACKGROUND: The seroepidemiology of Entamoeba histolytica in Mexico has been scantily studied. The aim of the study was to determine the seroprevalence and correlates of E. histolytica antibodies in adults in rural areas in Durango, Mexico.METHODS: Through a cross-sectional study, E. histolytica IgG antibodies were determined in 282 adults living in rural Durango, Mexico using an enzyme-linked immunoassay. In addition, seroprevalence association with the socio-demographic, housing conditions, and behavioral characteristics of the subjects studied was investigated.RESULTS: One hundred and eighteen (41.8%) of the 282 rural subjects had anti-E. histolytica IgG antibodies. Multivariate analysis showed that E. histolytica exposure was positively associated with source of drinking water (OR = 2.73; 95% CI: 1.33 - 5.58; P = 0.005), and poor education of the head of the family (OR = 1.53; 95% CI: 1.03 - 2.27; P = 0.03). In contrast, E. histolytica exposure was negatively associated with consumption of unpasteurized cow milk (OR = 0.55; 95% CI: 0.31 - 0.96; P = 0.03), and crowding at home (OR = 0.33; 95% CI: 0.17 - 0.64; P = 0.0009).CONCLUSIONS: The seroprevalence of E. histolytica infection found in adults in rural Durango is high compared with those reported in other Mexican populations. The correlates of E. histolytica seropositivity found in the present study may be useful for the planning of optimal preventive measures against E. histolytica infection.