The role of the inter-heavy chain disulfide bond in modulating the flexibility of immunoglobulin G antibody.
The role of the inter-heavy chain disulfide bond in modulating the flexibility of immunoglobulin G antibody.
复制标题
重链间二硫键在调节免疫球蛋白G抗体灵活性中的作用。
DOI：
10.1016/s0022-2836(77)80170-8
复制
发表时间：
1977
影响因子：
5.6
通讯作者：
R. Cathou
中科院分区：
文献类型：
--
作者：
L. Chan;R. Cathou
完整和还原的兔抗丹磺酰抗体的时间依赖性荧光各向异性的比较显示，重链间二硫键的还原显著增加了抗体分子的内部柔性。
Comparison of the time dependent fluoresecence anisotropies of intact and reduced rabbit anti-dansyl antibodies showed that reduction of the inter-heavy chain disulfide bond significantly increased the internal flexibility of the antibody molecules.