Acute exposure to fine particulate matter and cardiovascular hospital emergency room visits in Beijing, China
Acute exposure to fine particulate matter and cardiovascular hospital emergency room visits in Beijing, China
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DOI：
10.1016/j.envpol.2016.09.065
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发表时间：
2017-01-01
影响因子：
8.9
通讯作者：
Guo, Xiuhua
中科院分区：
文献类型：
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作者：
Xu, Qin;Wang, Shuo;Guo, Xiuhua
细颗粒物（PM2.5）空气污染爆发最近在中国频繁发生。然而，在中国，短期暴露于PM2.5和心血管疾病发病率之间的关联的证据仍然有限。本研究旨在评估北京市城区PM2.5与心血管疾病急诊就诊率之间的关系。收集了2013年1月1日至12月31日10家大型综合医院的心血管ERV每日计数。空气污染数据来自北京市环境保护局，包括17个监测站。在控制了季节性、星期几、公共假日、流感爆发和天气条件后，使用广义加性泊松模型来研究PM2.5和心血管ERV之间的关联。研究期间总共有56，221例心血管ERV。PM2.5的日平均浓度为102.1微克/立方米，范围为6.7微克/立方米至508.5微克/立方米。PM2.5每增加10 μ g/m3，滞后时心血管ERV增加0.14%（95%置信区间[CI]：0.01%-0.27%）。累积延迟估计值在滞后（0-5）时最大（0.30%，95% CI：0.09%-0.52%）。PM2.5每增加10 μ g/m3，每日ERV的百分比变化估计为0.56%。（95%CI：0.16%-0.95%）对于缺血性心脏病（IHD），在滞后期（0-1），0.81%（95%CI：0.05%-1.57%）;（0）时心力衰竭（HF）的发生率为1.21%（95%CI：0.27%-2.15%）。高温日（>11.01 ℃）PM2.5对IHD ERVs的影响显著高于低温日（
Fine particulate matter (PM2.5) air pollution outbreaks have recently occurred frequently in China. However, evidence of the associations between short-term exposure to PM2.5 and cardiovascular morbidity is still limited in China. This study aimed to evaluate the associations between PM2.5 and hospital emergency room visits (ERVs) for cardiovascular diseases in urban areas in Beijing. Daily counts of cardiovascular ERVs were collected from ten large general hospitals from Jan 1 to Dec 31, 2013. Air pollution data were obtained from the Beijing Environmental Protection Bureau including 17 monitoring stations. A generalized additive Poisson model was used to examine the associations between PM2.5 and cardiovascular ERVs after controlling for seasonality, day of the week, public holidays, influenza outbreaks, and weather conditions. In total, there were 56,221 cardiovascular ERVs during the study period. The daily mean PM2.5 concentration was 102.1 mu g/m(3), ranging from 6.7 mu g/m(3) to 508.5 mu g/m(3). Per 10 mu g/m(3) increase in PM2.5 was associated with a 0.14% (95% confidence interval [CI]: 0.01%-0.27%) increase in cardiovascular ERVs at lags. Cumulative delayed estimates were greatest at lag(0-5) (0.30%, 95% CI: 0.09% -0.52%). The estimates of percentage change in daily ERVs per 10 mu g/m(3) increase in PM2.5 were 0.56% (95%CI: 0.16%-0.95%) for ischemic heart disease (IHD) at lag(0-1), 0.81% (95%CI: 0.05%-1.57%) for heart rhythm disturbances (HRD) at lag(0-1) and 1.21% (95%CI: 0.27%-2.15%) for heart failure (HF) at lag(0), respectively. The effects of PM2.5 on IHD ERVs during high temperature days (>11.01 degrees C) were significantly higher than that on low temperature days (