DRUG DATA CODING AND ANALYSIS IN EPIDEMIOLOGIC STUDIES
DRUG DATA CODING AND ANALYSIS IN EPIDEMIOLOGIC STUDIES
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DOI：
10.1007/bf01719664
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发表时间：
1994-08-01
影响因子：
13.6
通讯作者：
CARBONIN, P
中科院分区：
文献类型：
--
作者：
PAHOR, M;CHRISCHILLES, EA;CARBONIN, P
在收集药物使用综合信息的流行病学研究中，处理大量商品名和通用名的复杂性可能会限制这些数据库的利用。本文展示了使用两种编码系统的具体优势，一种是最大限度地提高数据输入的效率，另一种是通过将药物成分组织成层次类别来促进分析。两个大型调查，一个在美国和一个在意大利，所使用的方法，描述：老年人流行病学研究（EPESE）和'Gruppo Italiano迪Farmacovigilanza内尔' Anziano'（GIFA）的既定人群。要将药物输入计算机化数据库，需要与药品名称匹配的代码。在EPESE中，处方药和非处方药分别使用药品信息编码系统（DPICS）和爱荷华州非处方药信息编码系统（INDPICS）进行编码。GIFA研究使用意大利卫生部（MINSAN）的编码系统，在意大利可获得的每种制剂均具有唯一的数字代码。为了简化分析过程，将药物输入代码转换为分层编码系统，并为特定药物成分、化学品和治疗类别提供唯一代码。EPESE和GIFA药物数据分别使用爱荷华州药物信息系统（IDIS）成分代码和解剖学治疗学和化学（ATC）代码进行编码。提供的例子显示编码利尿剂在这两项研究中，并证明这些系统的分析优势。
In epidemiologic studies that collect comprehensive information on medication use, the complexity of dealing with a large number of trade and generic names may limit the utilization of these data bases. This paper shows the specific advantage of using two coding systems, one to maximize efficiency of data entry, and the other to facilitate analysis by organizing the drug ingredients into hierarchical categories. The approach used by two large surveys, one in the USA and one in Italy, is described: the Established Populations for Epidemiologic Studies of the Elderly (EPESE) and the 'Gruppo Italiano di Farmacovigilanza nell' Anziano' (GIFA). To enter the medications into a computerized database, codes matching the drug product names are needed. In the EPESE the prescription and over the counter drug Products are coded with the Drug Products Information Coding System (DPICS) and the Iowa Nonprescription Drug Products Information Coding System (INDPICS), respectively. The GIFA study uses the coding system of the Italian Ministry of Health (MINSAN), with a unique numeric code for each drug product available in Italy. To simplify the analytical process the drug entry codes are converted into hierarchical coding systems with unique codes for specific drug ingredients, chemical and therapeutic categories. The EPESE and GIFA drug data are coded with the Iowa Drug Information System (IDIS) ingredient codes, and the Anatomical Therapeutic and chemical (ATC) codes, respectively. Examples are provided that show coding of diuretics in these two studies and demonstrate the analytic advantages of these systems.