Intergenerational health consequences of in utero exposure to maternal stress: Evidence from the 1980 Kwangju uprising
Intergenerational health consequences of in utero exposure to maternal stress: Evidence from the 1980 Kwangju uprising
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DOI：
10.1016/j.socscimed.2014.07.001
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发表时间：
2014-10-01
影响因子：
5.4
通讯作者：
Lee, Chulhee
中科院分区：
文献类型：
--
作者：
Lee, Chulhee
越来越多的证据表明，怀孕期间母亲的心理压力会对各种各样的后代产生负面影响。动物研究表明，怀孕期间母亲压力的负面影响会持续几代人，但证实这种影响在人类群体中存在的直接证据很少。本研究从光州起义（1980年5月18日至27日）中提取了母亲压力的代际影响的证据，该起义可以说是自1953年朝鲜战争结束以来发生在韩国的最血腥的事件。差异中差估计结果表明，宫内暴露于光州起义显著降低了子代出生体重和妊娠长度，增加了低出生体重和早产的风险。在怀孕的第二个三个月暴露在压力下对孙子的出生结果产生了最大的负面影响。(C) 2014 Elsevier Ltd.版权所有。
The evidence that demonstrates the negative effects of maternal psychological stress during pregnancy on a wide variety of offspring outcomes is growing. Animal studies suggest that negative influences of maternal stress during pregnancy persist across multiple generations, but the direct evidence to confirm that the effect is present among human populations is scarce. This study draws evidence on the inter-generational influences of maternal stress from the Kwangju uprising (May 18-27, 1980), arguably the bloodiest incident that occurred in South Korea since the end of the Korean War in 1953. The results of difference-in-difference estimations suggest that in utero exposure to the Kwangju uprising significantly diminished the offspring birth weight and length of gestation, and increased the risks of low birth weight and preterm birth. Exposure to stress during the second trimester of pregnancy exerted the strongest negative effect on grandchildren's birth outcomes. (C) 2014 Elsevier Ltd. All rights reserved.