A comparison of goodness of fit tests for age-related reference ranges

A comparison of goodness of fit tests for age-related reference ranges
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DOI:
10.1002/sim.1692
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发表时间:
2004-06-15
影响因子:
2
通讯作者:
Cole, TJ
Cole, TJ
中科院分区:
医学3区
文献类型:
--
作者:
Pan, H;Cole, TJ

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基于三次样条或基于核的平滑方法的年龄相关参考范围缺乏用于评估拟合优度的参数框架,因为比较具有不同平滑程度的模型的对数似然比的分布通常是未知的。在这种情况下,已经提出了几种方法来评估拟合优度:Healy的网格测试、Royston的Q测试和van Buuren的蠕虫图。在这里,我们比较各种方法的性能,包括Q检验的扩展,并展示它们如何与其他信息一起使用,包括拟合曲线的外观,以在荷兰大型数据集中为与年龄相关的身高和体重参考范围的模型选择提供信息。版权所有(C)2004 John Wiley Sons,Ltd.
Age-related reference ranges based on cubic spline or kernel-based smoothing methods lack a parametric framework with which to assess goodness of fit, as the distribution of the log-likelihood ratio comparing models with different degrees of smoothing is not known in general. Several methods have been proposed to assess goodness of fit in this case: Healy's grid test, Royston's Q tests and van Buuren's worm plot. Here we compare the performance of the various methods, including an extension of the Q tests, and show how they can be used, with other information including the appearance of the fitted curves, to inform the choice of model for age-related reference ranges of height and weight in a large Dutch data set. Copyright (C) 2004 John Wiley Sons, Ltd.